Evidence map›Paper›PMID 38352524›Full record

ArticlemedRxiv : the preprint server for health sciences2024

Factors associated with decreased anal sphincter tone and the accuracy of forced anal examinations to detect individuals having receptive anal intercourse: An observational study.

Alan G Nyitray, B R Simon Rosser, Aniruddha Hazra, Jenna Nitkowski, Derek Smith, Bridgett Brzezinski, Timothy J Ridolfi, John A Schneider, Elizabeth Y Chiao, Sandrine Sanos and 3 more

Registry-linked trialOpen access · greenAbstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04090060 (Determining the Accuracy of Self and Partner Anal Exams for Detecting Anal Abnormalities.), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04090060 nacompletednot on this map

Determining the Accuracy of Self and Partner Anal Exams for Detecting Anal Abnormalities.

TypeinterventionalSponsorMedical College of WisconsinRan2020 to 2023Enrolled718ConditionsAnal CancerArmsPractice Self-/Companion Exams, Control Arm
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 10 institutions in 2 countries.

Derek Smith
Bridgett BrzezinskiORCID 0009-0005-4465-2101
Timothy J RidolfiORCID 0000-0002-0177-752X
Elizabeth Y ChiaoORCID 0000-0001-5752-2916
Sandrine Sanos
Michael W Ross
Medical College of Wisconsin · USCase Western Reserve University · USChicago Department of Public Health · USCRO Laboratories (United States) · USMuhimbili University of Health and Allied Sciences · TZThe University of Texas at San Antonio · USThe University of Texas MD Anderson Cancer Center · USUniversity of Chicago · USUniversity of Minnesota · USUniversity of Minnesota Medical Center · US

Funding

Determining the accuracy of self- and partner anal exams for detecting anal abnormalities.R01CA232892 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI NYITRAY, ALAN GASPAR · 2018 to 2022
$3.2M
Annual anal sampling using DNA screening to identify men who have sex with men at increased risk for anal cancerR01CA215403 · NCI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI NYITRAY, ALAN GASPAR · 2017 to 2021
$2.8M
NCI NIH HHS R01 CA215403NCI NIH HHS R01 CA232892
6 · The paper itself

Abstract

Objective and Design: Forced anal examinations are used to prosecute sexual and gender minorities (SGM) in at least seven countries under the presumption that decreased sphincter tone, estimated by a finger inserted into the anal canal, can detect persons practicing receptive anal intercourse. In a cross-sectional analysis of the baseline data from a longitudinal study, we aimed to determine factors associated with sphincter tone and the accuracy of sphincter tonality to detect persons engaging in receptive anal intercourse. Setting: Clinicians in Chicago, Houston, and Milwaukee, USA conducted digital anal rectal examinations (DARE) on 838 participants, 94.0% of whom were cisgendered males. Clinicians used the Digital Rectal Examination Scoring System to score sphincter resting tone (RT) and squeeze tone (ST). On a separate survey, individuals reported their preferred position for anal intercourse: i.e., either always/mostly insertive anal intercourse, always/mostly receptive anal intercourse, or both receptive and insertive anal intercourse. Multivariable regression assessed factors associated with decreased sphincter tone while area under the Receiver Operating Characteristic curves (AUC) estimated the accuracy of sphincter tonality to detect receptive anal intercourse. Results: 11.3% had decreased RT (95/838) and 6.3% had decreased ST (53/838). The accuracy of DARE to detect any receptive anal intercourse was little better than random guessing (AUC 0.53, 95% CI 0.51 to 0.55, and AUC 0.51, 95% CI 0.49 to 0.53, respectively. RT and ST decreased with age regardless of sexual behavior (p Conclusions: Decreased sphincter tone is uncommon among SGM who prefer receptive anal intercourse. Given virtually no accuracy, a finger inserted into the anus has no utility to detect individuals practicing receptive anal intercourse and thus should not be used as such. Trial registration: NCT04090060. Summary Box:

Identifiers

PMID38352524
PMCPMC10862988
OpenAlexW4391452018

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.