Evidence map›Paper›PMID 38352502›Full record

ArticlebioRxiv : the preprint server for biology2024

Metapopulation model of phage therapy of an acute

Rogelio A Rodriguez-Gonzalez, Quentin Balacheff, Laurent Debarbieux, Jacopo Marchi, Joshua S Weitz

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Rogelio A Rodriguez-GonzalezInterdisciplinary Graduate Program in Quantitative Biosciences, Georgia Institute of Technology, Atlanta, Georgia, USA.ORCID 0000-0002-5460-4999
Quentin BalacheffCHU Felix Guyon, Service des maladies respiratoires, La Réunion, France.
Laurent DebarbieuxDepartment of Microbiology, Institut Pasteur, Paris, France.ORCID 0000-0001-6875-5758
Jacopo MarchiDepartment of Biology, University of Maryland, College Park, Maryland, USA.
Joshua S WeitzDepartment of Biology, University of Maryland, College Park, Maryland, USA.ORCID 0000-0002-3433-8312
Centre Hospitalier Universitaire de La Réunion · FRGeorgia Institute of Technology · USInstitut de Biologie de l'École Normale Supérieure · FRInstitut Pasteur · FRUniversity of Maryland, College Park · US

Funding

Synergistic control of acute respiratory pathogens by bacteriophage and the innate immune responseR01AI146592 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI DEBARBIEUX, LAURENT, WEITZ, JOSHUA · 2019 to 2023
$2.4M
NIAID NIH HHS R01 AI146592
6 · The paper itself

Abstract

Infections caused by multi-drug resistant (MDR) pathogenic bacteria are a global health threat. Phage therapy, which uses phage to kill bacterial pathogens, is increasingly used to treat patients infected by MDR bacteria. However, the therapeutic outcome of phage therapy may be limited by the emergence of phage resistance during treatment and/or by physical constraints that impede phage-bacteria interactions

Identifiers

PMID38352502
PMCPMC10862780
OpenAlexW4391444993

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.