Evidence map›Paper›PMID 38352448›Full record

ArticlebioRxiv : the preprint server for biology2024

Giant polyketide synthase enzymes biosynthesize a giant marine polyether biotoxin.

Timothy R Fallon, Vikram V Shende, Igor H Wierzbicki, Robert P Auber, David J Gonzalez, Jennifer H Wisecaver, Bradley S Moore

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Timothy R FallonCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography and University of California, San Diego; 9500 Gilman Dr #0204, La Jolla, CA 92093, USA.ORCID 0000-0002-3048-7679
Vikram V ShendeCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography and University of California, San Diego; 9500 Gilman Dr #0204, La Jolla, CA 92093, USA.ORCID 0000-0001-8396-6297
Igor H WierzbickiDepartment of Pharmacology, University of California, San Diego; 9500 Gilman Dr, La Jolla, CA 92093, USA.ORCID 0009-0004-1441-3233
Robert P AuberDepartment of Biochemistry, Purdue University; 175 S University St, West Lafayette, IN 47907, USA.ORCID 0000-0002-1442-7473
David J GonzalezDepartment of Pharmacology, University of California, San Diego; 9500 Gilman Dr, La Jolla, CA 92093, USA.ORCID 0000-0003-1423-5970
Jennifer H WisecaverDepartment of Biochemistry, Purdue University; 175 S University St, West Lafayette, IN 47907, USA.ORCID 0000-0001-6843-5906
Bradley S MooreCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography and University of California, San Diego; 9500 Gilman Dr #0204, La Jolla, CA 92093, USA.ORCID 0000-0002-4652-1253

Funding

Natural Product Genome MiningR01GM085770 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JENSEN, PAUL R, MOORE, BRADLEY S · 2009 to 2024
$5.8M
Illumina NovaSeq 6000 Sequencing SystemS10OD026929 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JEPSEN, KRISTEN LYNN · 2019 to 2019
$600k
Elucidating the Biosynthesis of a Model Ladder-Frame Polyether ToxinF32ES032276 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FALLON, TIMOTHY R · 2020 to 2023
$220k
Refactoring Soft Coral Diterpenoid BiosynthesisF32GM145146 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SHENDE, VIKRAM VIJAY · 2022 to 2024
$215k
NIEHS NIH HHS F32 ES032276NIGMS NIH HHS F32 GM145146NIGMS NIH HHS R01 GM085770NIH HHS S10 OD026929
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID38352448
PMCPMC10862718

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.