Evidence map›Paper›PMID 38352446›Full record

ArticlebioRxiv : the preprint server for biology2024

A spatial model of autophosphorylation of Ca

Thomas M Bartol, Mariam Ordyan, Terrence J Sejnowski, Padmini Rangamani, Mary B Kennedy

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Thomas M BartolThe Salk Institute for Biological Studies, La Jolla, CA.ORCID 0009-0002-2598-0052
Mariam OrdyanThe Salk Institute for Biological Studies, La Jolla, CA.
Terrence J SejnowskiThe Salk Institute for Biological Studies, La Jolla, CA.
Padmini RangamaniDepartment of Mechanical and Aerospace Engineering, University of California San Diego, La Jolla, CA.ORCID 0000-0001-5953-4347
Mary B KennedyDepartment of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA.ORCID 0000-0003-1369-0525
Salk Institute for Biological Studies · USCalifornia Institute of Technology · USUniversity of California San Diego · US

Funding

TrainingP41GM103712 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FAEDER, JAMES · 2012 to 2021
$16.3M
Binding of synGAP to PDZ domains of PSD-95 and its role in Intellectual Disability and Autism Spectrum Disorders caused by synGAP haploinsufficiencyR01MH115456 · NIMH · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI KENNEDY, MARY B · 2018 to 2021
$1.7M
CRCNS: Regulation of assembly and disassembly of the postsynaptic density during synaptic plasticity and its effect on AMPAR trappingR01MH129066 · NIMH · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI KENNEDY, MARY B, SEJNOWSKI, TERRENCE J · 2021 to 2024
$1.2M
CRCNS: Modeling Activation of CaMKII in SpinesR01DA030749 · NIDA · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI KENNEDY, MARY B, SEJNOWSKI, TERRENCE J · 2010 to 2013
$1.2M
NIDA NIH HHS R01 DA030749NIGMS NIH HHS P41 GM103712NIMH NIH HHS R01 MH115456NIMH NIH HHS R01 MH129066
6 · The paper itself

Abstract

Long-term potentiation (LTP) is a biochemical process that underlies learning in excitatory glutamatergic synapses in the Central Nervous System (CNS). The critical early driver of LTP is autophosphorylation of the abundant postsynaptic enzyme, Ca

Identifiers

PMID38352446
PMCPMC10862815
OpenAlexW4391511898

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.