Evidence map›Paper›PMID 38352244›Full record

ReviewFrontiers in allergy2023

Pre-asthma: a useful concept for prevention and disease-modification? A EUFOREA paper. Part 1-allergic asthma.

G K Scadding, M McDonald, V Backer, G Scadding, M Bernal-Sprekelsen, D M Conti, E De Corso, Z Diamant, C Gray, C Hopkins and 12 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in allergy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

G K ScaddingDepartment of Allergy & Rhinology, Royal National ENT Hospital, London, United Kingdom.
M McDonaldThe Allergy Clinic, Blairgowrie, Randburg, South Africa.
V BackerDepartment of Otorhinolaryngology, Head & Neck Surgery, and Audiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark.
G ScaddingAllergy, Royal Brompton Hospital, London, United Kingdom.
M Bernal-SprekelsenHead of ORL-Deptartment, Clinic Barcelona, Barcelona, Spain.
D M ContiThe European Forum for Research and Education in Allergy and Airway Diseases Scientific Expert Team Members, Brussels, Belgium.
E De CorsoOtolaryngology Head and Neck Surgery, A. Gemelli University Hospital Foundation IRCCS, Rome, Italy.
Z DiamantDepartment of Respiratory Medicine & Allergology, Institute for Clinical Science, Skane University Hospital, Lund University, Lund, Sweden.
C GrayPaediatric Allergist, Red Cross Children's Hospital and University of Cape Town, Cape Town, South Africa.
C HopkinsDepartment of Rhinology and Skull Base Surgery, Guy's and St Thomas' Hospital NHS Foundation Trust, London, United Kingdom.
M JesenakDepartment of Clinical Immunology and Allergology, University Teaching Hospital in Martin, Martin, Slovakia.
P JohansenDepartment of Dermatology, University of Zurich, Zurich, Switzerland.
J KappenDepartment of Pulmonology, STZ Centre of Excellence for Asthma, COPD and Respiratory Allergy, Franciscus Gasthuis & Vlietland, Rotterdam, Netherlands.
J MullolRhinology Unit and Smell Clinic, ENT Department, Hospital Clínic, FRCB-IDIBAPS, Universitat de Barcelona, CIBERES, Barcelona, Spain.
D PriceObservational and Pragmatic Research Institute, Singapore, Singapore.
S QuirceDepartment of Allergy, La Paz University Hospital, IdiPAZ, Madrid, Spain.
S ReitsmaDepartment of Otorhinolarynogology and Head/Neck Surgery, Amsterdam University Medical Centres, Location AMC, University of Amsterdam, Amsterdam, Netherlands.
S SalmiDepartment of Otorhinolaryngology, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland.
B SeniorDepartment of Otolaryngology/Head and Neck Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
J P ThyssenDepartment of Dermatology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
U WahnFormer Head of the Department for Pediatric Pneumology and Immunology, Charite University Medicine, Berlin, Germany.
P W HellingsDepartment of Otorhinolaryngology-Head and Neck Surgery, University Hospitals, Leuven, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asthma, which affects some 300 million people worldwide and caused 455,000 deaths in 2019, is a significant burden to suffers and to society. It is the most common chronic disease in children and represents one of the major causes for years lived with disability. Significant efforts are made by organizations such as WHO in improving the diagnosis, treatment and monitoring of asthma. However asthma prevention has been less studied. Currently there is a concept of pre- diabetes which allows a reduction in full blown diabetes if diet and exercise are undertaken. Similar predictive states are found in Alzheimer's and Parkinson's diseases. In this paper we explore the possibilities for asthma prevention, both at population level and also investigate the possibility of defining a state of pre-asthma, in which intensive treatment could reduce progression to asthma. Since asthma is a heterogeneous condition, this paper is concerned with allergic asthma. A subsequent one will deal with late onset eosinophilic asthma.

Indexed as

asthmaasthma natural historypre-asthmapredispositionquality of liferisk factors

Identifiers

PMID38352244
PMCPMC10863454

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.