Evidence map›Paper›PMID 38352214›Full record

ArticleNutrition research and practice2024

Positive effects of anthocyanin-rich mulberry milk on mental health problems in the working population: an open-label study.

Poonsri Rangseekajee, Nawanant Piyavhatkul, Jintanaporn Wattanathorn, Wipawee Thukham-Mee, Pongsatorn Paholpak

Abstract read
In one paragraph

Article in Nutrition research and practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Review
  4. Article
  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Poonsri RangseekajeeResearch Institute for High Human Performance and Health Promotion, Khon Kaen University, Khon Kaen 40000, Thailand.ORCID https://orcid.org/0000-0001-8565-748X
Nawanant PiyavhatkulResearch Institute for High Human Performance and Health Promotion, Khon Kaen University, Khon Kaen 40000, Thailand.ORCID https://orcid.org/0000-0002-0041-4241
Jintanaporn WattanathornResearch Institute for High Human Performance and Health Promotion, Khon Kaen University, Khon Kaen 40000, Thailand.ORCID https://orcid.org/0000-0002-7383-2348
Wipawee Thukham-MeeResearch Institute for High Human Performance and Health Promotion, Khon Kaen University, Khon Kaen 40000, Thailand.ORCID https://orcid.org/0000-0001-6923-396X
Pongsatorn PaholpakResearch Institute for High Human Performance and Health Promotion, Khon Kaen University, Khon Kaen 40000, Thailand.ORCID https://orcid.org/0000-0003-0408-8460

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesDepression and anxiety are common mental health problems. Anthocyanins from berries might have an inhibitory effect on monoamine oxidase (MAO) enzymes and alleviate various mood and anxiety symptoms. This study examined the effects of a daily supplement of an anthocyanin-rich product on mental health problems. SUBJECTS/

methodsThis study was a secondary analysis from a randomized, 6-week, open-label trial in 300 healthy participants aged 18-60 years who consumed 1 or 2 servings of anthocyanin-rich mulberry milk daily. The General Health Questionnaire-28 (GHQ-28) and Hospital Anxiety and Depression Scale (HADS) were used to monitor mental health problems. In addition, the saliva activity levels of MAO-A, MAO-B, and cortisol were examined at the baseline and after 6 weeks.

resultsThe total scores of the GHQ-28 and HADS and all their subscales decreased in both groups (all

conclusionsDaily consumption of anthocyanin-rich mulberry milk possibly improves mental health problems by reducing depressive and anxiety symptoms in the working population. The suppression of MAO-A activity is a possible underlying mechanism. Trial Registration: Thai Clinical Trial Registration: #TCTR20201031002.

Indexed as

anthocyaninsanxietyDepressionmulberry

Identifiers

PMID38352214
PMCPMC10861345

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.