Evidence map›Paper›PMID 38352038›Full record

ArticleFrontiers in veterinary science2024

Adjuvants influence the immune cell populations present at the injection site granuloma induced by whole-cell inactivated paratuberculosis vaccines in sheep.

Miguel Criado, Luis E Reyes, Juan F García Marín, Daniel Gutiérrez-Expósito, David Zapico, José Espinosa, Valentín Pérez

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Miguel CriadoDepartamento de Sanidad Animal, Facultad de Veterinaria, Universidad de León, León, Spain.
Luis E ReyesDepartamento de Sanidad Animal, Facultad de Veterinaria, Universidad de León, León, Spain.
Juan F García MarínDepartamento de Sanidad Animal, Facultad de Veterinaria, Universidad de León, León, Spain.
Daniel Gutiérrez-ExpósitoDepartamento de Sanidad Animal, Facultad de Veterinaria, Universidad de León, León, Spain.
David ZapicoDepartamento de Sanidad Animal, Facultad de Veterinaria, Universidad de León, León, Spain.
José EspinosaDepartamento de Sanidad Animal, Facultad de Veterinaria, Universidad de León, León, Spain.
Valentín PérezDepartamento de Sanidad Animal, Facultad de Veterinaria, Universidad de León, León, Spain.
Universidad de León · ESInstituto de Ganadería de Montaña · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccination is the most effective tool for paratuberculosis control. Currently, available vaccines prevent the progression of clinical disease in most animals but do not fully protect them against infection and induce the formation of an injection site granuloma. The precise mechanisms that operate in response to vaccination and granuloma development, as well as the effect that adjuvants could trigger, have not been fully investigated. Therefore, this study aimed to investigate the injection site granulomas induced by two inactivated paratuberculosis vaccines, which differ in the adjuvant employed. Two groups of 45-day-old lambs were immunized with two commercially available vaccines-one (

Indexed as

adjuvantsgranulomaGudairparatuberculosisSilirumvaccine injection-site

Identifiers

PMID38352038
PMCPMC10861745
OpenAlexW4391358730

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.