Evidence map›Paper›PMID 38351986›Full record

ArticleJTCVS techniques2024

Mitral valve repair using leaflet expansion and subpartial annuloplasty in children.

Per Wierup, Jens Johansson Ramgren, Johan Sjögren, Kiet Tran Phan, Igor Zindovic, Shahab Nozohoor, Lea Christierson, Nina Hakacova

Open access · goldAbstract read
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Article in JTCVS techniques, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Per WierupDepartment of Pediatric Heart Surgery, Skane University Hospital, Lund, Sweden.
Jens Johansson RamgrenDepartment of Pediatric Heart Surgery, Skane University Hospital, Lund, Sweden.
Johan SjögrenDepartment of Cardiothoracic Surgery, Skane University Hospital, Lund, Sweden.
Kiet Tran PhanDepartment of Pediatric Heart Surgery, Skane University Hospital, Lund, Sweden.
Igor ZindovicDepartment of Cardiothoracic Surgery, Skane University Hospital, Lund, Sweden.
Shahab NozohoorDepartment of Cardiothoracic Surgery, Skane University Hospital, Lund, Sweden.
Lea ChristiersonDepartment of Pediatric Cardiology, Skane University Hospital, Lund, Sweden.
Nina HakacovaDepartment of Pediatric Cardiology, Skane University Hospital, Lund, Sweden.
Medtronic (United States) · USLund University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Mitral valve reconstruction in the pediatric population is a challenge due to the frequent combination of annular dilatation and leaflet restriction and the need for growth. We present a novel strategy using leaflet expansion and subpartial annuloplasty with polytetrafluoroethylene reinforcement. Methods: From January 2014 through May 2021, 11 children aged 5 months to 14 years (median, 24 months) underwent elective mitral valve repair due to severe mitral valve regurgitation. The mitral valve abnormalities included congenital malformations (n = 7), postoperative leakage following commissurotomy (n = 1), and functional mitral valve regurgitation due to dilated cardiomyopathy (n = 3). Surgery consisted of leaflet expansions with autologous, untreated pericardium and subpartial annuloplasty with polytetrafluoroethylene reinforcement. Results: All children survived their surgeries with uneventful postoperative courses, except for 1 patient who needed an early reoperation to resolve a functional stenosis due to a spinnaker phenomenon. At discharge, mean gradient was 3.5 ± 3.9 mm Hg, with trivial mitral regurgitation in 9 patients (82%). All patients were alive and asymptomatic during the median follow-up of 3 years (range, 1-7 years). Their echocardiographic data showed a mean transmitral gradient of 4.4 ± 1.7 mm Hg and remained unchanged. Residual mitral valve regurgitation was trivial or mild in 9 patients (82%) and moderate in 2 patients (18%). Conclusions: Leaflet expansion with autologous pericardium and subpartial annuloplasty with polytetrafluoroethylene reinforcement for mitral regurgitation in the pediatric population gives stable and satisfactory results both early and at intermediate follow-up, permitting growth of the mitral valve.

Indexed as

congenitalleaflet expansionmitral regurgitationneochordaepediatric

Identifiers

PMID38351986
PMCPMC10859564
OpenAlexW4388020481

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.