Evidence map›Paper›PMID 38351953›Full record

ArticleTherapeutics and clinical risk management2024

Minimally Invasive Treatment of Chyle Leak After Thyroidectomy and Cervical Lymph Node Dissection in Patients with Thyroid Carcinoma: Results of a Study Involving 36 Patients.

Nguyen Ngoc Cuong, Le Hoan, Thieu Thi Tra My, Doan Tien Luu, Le Tuan Linh, Pham Hong Canh, Trieu Quoc Tinh, Tran Nguyen Khanh Chi, Nguyen Quang Trung, Tran Quoc Hoa

Open access · goldAbstract read
In one paragraph

Article in Therapeutics and clinical risk management, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Nguyen Ngoc Cuong *Diagnostic Imaging and Interventional Center, Hanoi Medical University Hospital, Ha Noi, Viet Nam.ORCID 0000-0001-8809-9583
Le Hoan *Respiratory Department, Hanoi Medical University Hospital, Ha Noi, Viet Nam.ORCID 0000-0002-3514-7235
Thieu Thi Tra MyDiagnostic Imaging and Nuclear Medicine Department, Vinmec Times City International Hospital, Ha Noi, Viet Nam.ORCID 0000-0001-5894-706X
Doan Tien LuuDiagnostic Imaging and Interventional Center, Hanoi Medical University Hospital, Ha Noi, Viet Nam.
Le Tuan LinhDiagnostic Imaging and Interventional Center, Hanoi Medical University Hospital, Ha Noi, Viet Nam.
Pham Hong CanhDiagnostic Imaging and Interventional Center, Hanoi Medical University Hospital, Ha Noi, Viet Nam.
Trieu Quoc TinhDiagnostic Imaging and Interventional Center, Hanoi Medical University Hospital, Ha Noi, Viet Nam.
Tran Nguyen Khanh ChiDiagnostic Imaging and Interventional Center, Hanoi Medical University Hospital, Ha Noi, Viet Nam.
Nguyen Quang TrungDiagnostic Imaging and Interventional Center, Hanoi Medical University Hospital, Ha Noi, Viet Nam.
Tran Quoc HoaUrology Surgery department, Hanoi Medical university, Ha Noi, Viet Nam.
Hanoi Medical University Hospital · VNHanoi Medical University · VNVinmec International Hospital · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Chyle leak (CL) after head and neck surgery is a rare but well-known complication. In patients with high-output leakage, the treatment can be complicated. This study aims to report on a recent innovation in lymphatic intervention for treating such patients. Materials and Methods: A retrospective review of 36 patients with chyle leak after neck surgery for thyroid cancer was conducted to assess the efficacy of percutaneous lymphatic embolization and thoracic duct (TD) disruption. Results: Antegrade catheterization of the thoracic duct was achieved in 31 of 36 patients (86.1%). Therefore, embolization of the thoracic duct and thoracic duct branches was performed in 26 and 5 patients, respectively. In 5 cases of unsuccessful antegrade catheterization into the thoracic duct, transcervical access embolization was performed in 2 patients, and TD disruption (TDD) was performed in 3 patients. The pooled overall technical success rate of lymphatic embolization was 33/36 patients (91.7%). One patient who underwent thoracic duct embolization (TDE) with technical success (1/33 patients) but clinical failure had additional treatment directly sclerosing the TD under computed tomography scan. Cervical fluid collection sclerotherapy was done in 7 patients as an additional treatment. Resolution of the chyle leak after procedures was observed in all patients (100%). The mean time to resolution was 3 days (1-7 days). There was no complication intra and after procedures. Conclusion: TDE, selective TD branches embolization and TDD are safe and effective minimally invasive treatments for CL post-surgery for thyroid carcinoma. Sclerosing cervical fluid collection contributes to clinical success.

Indexed as

chyle leaksclerotherapythoracic duct disruptionthoracic duct embolizationthyroid cancerthyroidectomy

Identifiers

PMID38351953
PMCPMC10863455
OpenAlexW4392731177

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.