SynthesisTropical medicine & international health : TM & IH2024
Global distribution of Leptospira serovar isolations and detections from animal host species: A systematic review and online database.
Synthesis in Tropical medicine & international health : TM & IH, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 34 citations in OpenAlex.
- First report of seropositivity to pathogenic Leptospira in backyard hens: potential poultry health issue and zoonotic risk.Poultry science · 2026Article
- Environmental Distribution of Pathogenic Leptospira spp. in Subtropical Rivers of Japan and Implications for Human Infection.Tropical medicine & international health : TM & IH · 2026Article
- Genetic Epidemiology of Bovine Leptospirosis: A Global Perspective from Sequence and Genome Datasets.Animals : an open access journal from MDPI · 2026Article
- Host adaptation drives genome evolution and virulence diversification in a bacterial zoonotic pathogen.bioRxiv : the preprint server for biology · 2026Article
- A systematic review and meta-analysis ofOne health (Amsterdam, Netherlands) · 2026Review
- Molecular detection and phylogenetic characterization ofOpen veterinary journal · 2026Article
- Epidemiological study of leptospiral interaction in bovine farms in rural areas of Colombia: A One Health approach.PLoS neglected tropical diseases · 2026Article
- Revisiting genital leptospirosis in large animals: impacts on reproductive health, diagnostic challenges, and future directions.Journal of clinical microbiology · 2026Review
- TheInfection and immunity · 2026Article
- Serological and molecular evidence of Leptospira spp. in martens from Poland.BMC veterinary research · 2026Article
- Leptospirosis Prevalence and Risk Factors Among Patients Presenting With Fever to 4 Healthcare Sites in Sub-Saharan Africa and South East Asia: An International Multisite Observational and Nested Case-Control Study.The Journal of infectious diseases · 2026Observational
- Integrative assessment of species-level genetic markers for the diagnosis of pathogenicFrontiers in public health · 2026Article
- Epidemiological characteristics of leptospirosis and serological surveillance among reservoir animals and healthy populations in Fujian, China, 2004-2024.Frontiers in public health · 2026Article
- Leptospirosis in the Caribbean Region between 2000 and 2022: A scoping review of morbidity and mortality.PLoS neglected tropical diseases · 2026Article
- In vitro and in vivo endothelial interactions of Leptospira species are markers of virulence.PLoS neglected tropical diseases · 2026Article
- A Guidance for Diagnosis, Control Measures, and Surveillance of Leptospirosis in Non-Human Primates From a Veterinary Perspective in a One-Health Approach.Journal of medical primatology · 2025Review
- Human leptospirosis in the central division of Fiji: a retrospective epidemiological study.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2025Article
- Endemicity, Clinical Features, Risk Factors, and the Potential for Severe Infection inTropical medicine and infectious disease · 2025Article
- High-throughput microfluidic real-time PCR as a promising tool in disease ecology.The Journal of animal ecology · 2025Article
- Shaping the future ofJournal of medical microbiology · 2025Review
Corrections and comments
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Authors and funding
16 authors at 9 institutions in 7 countries.
Funding
Abstract
objectivesLeptospira, the spirochaete causing leptospirosis, can be classified into >250 antigenically distinct serovars. Although knowledge of the animal host species and geographic distribution of Leptospira serovars is critical to understand the human and animal epidemiology of leptospirosis, current data are fragmented. We aimed to systematically review, the literature on animal host species and geographic distribution of Leptospira serovars to examine associations between serovars with animal host species and regions and to identify geographic regions in need of study.
methodsNine library databases were searched from inception through 9 March 2023 using keywords including Leptospira, animal, and a list of serovars. We sought reports of detection of Leptospira, from any animal, characterised by cross agglutinin absorption test, monoclonal antibody typing, serum factor analysis, or pulsed-field gel electrophoresis to identify the serovar.
resultsWe included 409 reports, published from 1927 through 2022, yielding data on 154 Leptospira serovars. The reports included data from 66 (26.5%) of 249 countries. Detections were from 144 animal host species including 135 (93.8%) from the class Mammalia, 5 (3.5%) from Amphibia, 3 (2.1%) from Reptilia, and 1 (0.7%) from Arachnida. Across the animal host species, Leptospira serovars that were detected in the largest number of animal species included Grippotyphosa (n = 39), Icterohaemorrhagiae (n = 29), Pomona (n = 28), Australis (n = 25), and Ballum (n = 25). Of serovars, 76 were detected in a single animal host species. We created an online database to identify animal host species for each serovar by country.
conclusionsWe found that many countries have few or no Leptospira serovars detected from animal host species and that many serovars were detected from a single animal species. Our study highlights the importance of efforts to identify animal host species of leptospirosis, especially in places with a high incidence of human leptospirosis. We provide an updated resource for leptospirosis researchers.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.