Evidence map›Paper›PMID 38351389›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2024

Prognostic value of baseline and interim [

Mikhail Ya Yadgarov, M M Dunaykin, G I Shestopalov, C Kailash, E D Kireeva, N V Myakova, Yu N Likar

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Spleens With Disseminated Lymphoma Exhibit Higher Standardized Uptake Value Maximum, Metabolic Tumor Volumes, and Total Lesion Glycolysis on Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography.Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association · 2026
    Article
  4. Role ofTurkish journal of haematology : official journal of Turkish Society of Haematology · 2026
    Article
  5. Baseline and interimCancer imaging : the official publication of the International Cancer Imaging Society · 2026
    Article
  6. [European journal of nuclear medicine and molecular imaging · 2026
    Article
  7. Assessing the intracranial metabolic score as a novel prognostic tool in primary CNS lymphoma with end of induction-chemotherapyCancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Article
  8. Semiquantitative 2-[Frontiers in medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mikhail Ya YadgarovDmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia. mikhail.yadgarov@mail.ru.ORCID 0000-0003-3792-1682
M M DunaykinDmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia.ORCID 0000-0001-9830-5686
G I ShestopalovDmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia.ORCID 0000-0002-2410-2867
C KailashDmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia.ORCID 0000-0002-7427-4560
E D KireevaDmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia.ORCID 0000-0003-3990-8879
N V MyakovaDmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia.ORCID 0000-0002-4779-1896
Yu N LikarDmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia.ORCID 0000-0002-6158-2222
Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology · RUPirogov Russian National Research Medical University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHodgkin lymphoma (HL) in pediatric populations has a high survival rate but poses risks for long-term morbidities. Although [

methodsA single-center, retrospective study included pediatric patients diagnosed with HL between 2016 and 2023 treated according to EuroNet-PHL-C1 and DAL/GPOH-HD protocols. Patients underwent baseline and interim PET/CT scans after two chemotherapy cycles. Event-free survival (EFS) was the primary endpoint, Deauville score was the secondary endpoint. Quantitative [

resultsA total of 115 patients (50 males, median age 14.2 years) were studied, with a median follow-up period of 35 months. During this period, 16 cases (13.9%) of relapse or progression were noted. Baseline and interim MTV 2.5, MTV 41%, TLG 2.5, and TLG 41%, along with interim SUVmax, were significantly associated with worse EFS and correlated with post-treatment Deauville scores. In multivariable analysis, interim MTV 2.5 > 0 ml (adj. hazard ratio, HR: 3.89, p = 0.009) and interim TLG 41% ≥ 30 g (adj. HR: 7.98, p = 0.006) were independent risk factors for EFS.

conclusionBaseline and interim [

Indexed as

Fluorodeoxyglucose F18Hodgkin DiseaseAdolescentChildChild, PreschoolFemaleHumansMalePositron Emission Tomography Computed TomographyPrognosisRetrospective StudiesFluorodeoxyglucose F18[18F]FDG PETEvent-free survivalMetabolic tumor volumePediatric Hodgkin LymphomaSegmentationTotal lesion glycolysis

Identifiers

PMID38351389
OpenAlexW4392783892

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.