Evidence map›Paper›PMID 38351361›Full record

ArticleMikrochimica acta2024

High-affinity truncated aptamers for detection of Cronobacter spp with magnetic separation-assisted DNAzyme-driven 3D DNA walker.

Ningru Yang, Ning Ding, Shuo Qi, Zixuan Shang, Pengfei Ma, Imran Mahmood Khan, Zhouping Wang, Yu Xia, Yin Zhang, Lili Zhang

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
6.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Ningru YangState Key Laboratory of Food Science and Resources, School of Food Science and Technology, International Joint Laboratory On Food Safety, Jiangnan University, Wuxi, 214122, China.
Ning DingState Key Laboratory of Food Science and Resources, School of Food Science and Technology, International Joint Laboratory On Food Safety, Jiangnan University, Wuxi, 214122, China.
Shuo QiState Key Laboratory of Food Science and Resources, School of Food Science and Technology, International Joint Laboratory On Food Safety, Jiangnan University, Wuxi, 214122, China.
Zixuan ShangState Key Laboratory of Food Science and Resources, School of Food Science and Technology, International Joint Laboratory On Food Safety, Jiangnan University, Wuxi, 214122, China.
Pengfei MaState Key Laboratory of Food Science and Resources, School of Food Science and Technology, International Joint Laboratory On Food Safety, Jiangnan University, Wuxi, 214122, China.
Imran Mahmood KhanState Key Laboratory of Food Science and Resources, School of Food Science and Technology, International Joint Laboratory On Food Safety, Jiangnan University, Wuxi, 214122, China.
Zhouping WangState Key Laboratory of Food Science and Resources, School of Food Science and Technology, International Joint Laboratory On Food Safety, Jiangnan University, Wuxi, 214122, China. wangzp@jiangnan.edu.cn.
Yu XiaState Key Laboratory of Food Science and Resources, School of Food Science and Technology, International Joint Laboratory On Food Safety, Jiangnan University, Wuxi, 214122, China.
Yin ZhangKey Laboratory of Meat Processing of Sichuan, Chengdu University, Chengdu, 610106, China.
Lili ZhangKey Laboratory of Food Quality and Safety of Jiangsu Province-State Key Laboratory Breeding Base, Institute of Food Safety and Nutrition, Jiangsu Academy of Agricultural Sciences, Nanjing, 210014, China.
Jiangnan University · CNState Key Laboratory of Food Science and Technology · CNChengdu University · CNJiangsu Academy of Agricultural Sciences · CN

Funding

International Science and Technology Cooperation Program of Jiangsu Province BE2022324the National First-class Discipline Program of Food Science and Technology JUFSTR20180303the National Key Research and Development Program of China 2021YFE0101800the National Natural Science Foundation of China 3221101215the National Natural Science Foundation of China 32372423the S&T Plan Project of Jiangsu Provincial BE2022324
6 · The paper itself

Abstract

After optimizing the original aptamer sequence by truncation strategy, a magnetic separation-assisted DNAzyme-driven 3D DNA walker fluorescent aptasensor was developed for detecting the food-borne pathogen Cronobacter species. Iron oxide magnetic nanoparticles (MNPs) modified with a hybrid of truncated aptamer probe and DNAzyme strand (AP-E1) denoted as MNPs@AP-E1, were employed as capture probes. Simultaneously, a DNAzyme-driven 3D-DNA walker was utilized as the signal amplification element. The substrate strand (Sub) was conjugated with the gold nanoparticles (AuNPs), resulting in the formation of AuNPs@Sub, which served as a 3D walking track. In the presence of the target bacteria and Mg

Indexed as

Aptamers, NucleotideBiosensing TechniquesCronobacterDNA, CatalyticMetal NanoparticlesDNAGoldLimit of DetectionAptamers, NucleotideDNADNA, CatalyticGoldAptamerAu nanoparticlesCronobacter spp.DNA walkerFluorescence detectionTruncation

Identifiers

PMID38351361
OpenAlexW4391799713

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.