ArticleBiological trace element research2024
Therapeutic Potential of Green Synthesized Silver Nanoparticles for Promoting Wound-Healing Process in Diabetic Mice.
Article in Biological trace element research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 12 citations in OpenAlex.
- Biosynthesis of ecofriendly antibacterial nanoparticles with healing effects in a murine diabetic skin infection model.Scientific reports · 2026Article
- Advanced Bioinspired Silver Nanoparticles Integrated into Polyherbal Gel for Enhanced Diabetic Foot Ulcer Regeneration.Biological trace element research · 2026Article
- Recent Advances of Silver Nanoparticles in Wound Healing: Evaluation of In Vivo and In Vitro Studies.International journal of molecular sciences · 2025Review
- Biosynthesized Silver Nanoparticles and Their Antidiabetic Potential.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Therapies and delivery systems for diabetic wound care: current insights and future directions.Frontiers in pharmacology · 2025Review
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetes is a serious metabolic disorder characterized by abnormal glucose levels in the body. Delayed wound healing is a severe diabetes complication. Nanotechnology represents the latest advancement in treating diabetic wounds through nanoparticles (NPs). In this study, silver nanoparticles (AgNPs) were synthesized using a green method involving cucumber pulp extract. The synthesis was confirmed using techniques including ultraviolet-visible spectrophotometry (UV-Vis), Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), scanning electron microscopy (SEM), and energy dispersive X-ray (EDX). To evaluate wound-healing properties, mouse models were utilized with wounds induced by excision on the dorsal surface. An ointment containing silver nanoparticles was applied to assess its healing potential. Additionally, antibacterial and antioxidant activities were examined using agar well diffusion and DPPH scavenging methods, respectively. The results demonstrated that the ointment prepared with green synthesized AgNPs effectively healed the wounds within 15 days, while also exhibiting antibacterial and antioxidant properties. Therefore, it can be concluded that due to its efficacy in biological activities, silver nanoparticles can be employed in the treatment of diabetic wounds.
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Registered trials
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