Evidence map›Paper›PMID 38351306›Full record

ArticleScientific reports2024

The six-minute step test can predict COPD exacerbations: a 36-month follow-up study.

Aldair Darlan Santos-de-Araújo, Cássia da Luz Goulart, Renan Shida Marinho, Izadora Moraes Dourado, Renata Gonçalves Mendes, Meliza Goi Roscani, Daniela Bassi-Dibai, Shane A Phillips, Ross Arena, Audrey Borghi-Silva

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Predictors of Acute Exacerbations in COPD: A Systematic Review.International journal of chronic obstructive pulmonary disease · 2026
    Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Aldair Darlan Santos-de-AraújoCardiopulmonary Physiotherapy Laboratory, Universidade Federal de São Carlos, São Carlos, SP, 13565-905, Brazil.
Cássia da Luz GoulartCardiopulmonary Physiotherapy Laboratory, Universidade Federal de São Carlos, São Carlos, SP, 13565-905, Brazil.
Renan Shida MarinhoCardiopulmonary Physiotherapy Laboratory, Universidade Federal de São Carlos, São Carlos, SP, 13565-905, Brazil.
Izadora Moraes DouradoCardiopulmonary Physiotherapy Laboratory, Universidade Federal de São Carlos, São Carlos, SP, 13565-905, Brazil.
Renata Gonçalves MendesCardiopulmonary Physiotherapy Laboratory, Universidade Federal de São Carlos, São Carlos, SP, 13565-905, Brazil.
Meliza Goi RoscaniDepartment of Medicine, Universidade Federal de São Carlos (UFSCar), Sao Carlos, SP, Brazil.
Daniela Bassi-DibaiPostgraduate Program in Management in Health Programs and Services, Universidade CEUMA, São Luís, MA, Brazil.
Shane A PhillipsDepartment of Physical Therapy, College of Applied Health Sciences, University of Illinois Chicago, Chicago, IL, USA.
Ross ArenaDepartment of Physical Therapy, College of Applied Health Sciences, University of Illinois Chicago, Chicago, IL, USA.
Audrey Borghi-SilvaCardiopulmonary Physiotherapy Laboratory, Universidade Federal de São Carlos, São Carlos, SP, 13565-905, Brazil. audrey@ufscar.br.
Universidade Federal de São Carlos · BRUniversity of Illinois Chicago · USCentro Universitário do Maranhão · BR

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 15/26501-1
6 · The paper itself

Abstract

The six-minute step test (6MST) has been shown to be effective in assessing exercise capacity in individuals with COPD regardless of severity and, despite its easy execution, accessibility and validity, information on the prognostic power of this test remains uncertain. The aim of this study is to investigate whether the 6MST can predict the occurrence of exacerbations in patients with COPD. This is a prospective cohort study with a 36-month follow-up in patients with COPD. All patients completed a clinical assessment, followed by pulmonary function testing and a 6MST. The 6MST was performed on a 20 cm high step; heart rate, blood pressure, oxygen saturation, BORG dyspnea and fatigue were collected. Sixty-four patients were included in the study, the majority being elderly men. Performance on the 6MST demonstrated lower performance compared to normative values proposed in the literature, indicating a reduced functional capacity. Kaplan Meier analysis revealed that ≤ 59 steps climbed during the 6MST was a strong predictor of COPD exacerbation over a 36-month follow-up. We have identified a minimal threshold number of steps (≤ 59) obtained through the 6MST may be able predict the risk of exacerbations in patients with COPD.

Indexed as

Exercise TestPulmonary Disease, Chronic ObstructiveAgedFollow-Up StudiesHumansMaleProspective StudiesRespiratory Function TestsChronic obstructive pulmonary diseaseExacerbationFunctional capacitySix-minute step test

Identifiers

PMID38351306
PMCPMC10864352
OpenAlexW4391779934

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.