Evidence map›Paper›PMID 38351260›Full record

ArticleRadiological physics and technology2024

3D-printed boluses for radiotherapy: influence of geometrical and printing parameters on dosimetric characterization and air gap evaluation.

Simone Giovanni Gugliandolo, Shabarish Purushothaman Pillai, Shankar Rajendran, Maria Giulia Vincini, Matteo Pepa, Floriana Pansini, Mattia Zaffaroni, Giulia Marvaso, Daniela Alterio, Andrea Vavassori and 6 more

Abstract read
In one paragraph

Article in Radiological physics and technology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Simone Giovanni GugliandoloDepartment of Mechanical Engineering, Politecnico di Milano, Via La Masa, 1, 20156, Milano, Italy.
Shabarish Purushothaman PillaiDepartment of Mechanical Engineering, Politecnico di Milano, Via La Masa, 1, 20156, Milano, Italy.
Shankar RajendranDepartment of Mechanical Engineering, Politecnico di Milano, Via La Masa, 1, 20156, Milano, Italy.
Maria Giulia VinciniDivision of Radiation Oncology, IEO European Institute of Oncology, IRCCS, Milano, Italy.
Matteo PepaDivision of Radiation Oncology, IEO European Institute of Oncology, IRCCS, Milano, Italy.
Floriana PansiniUnit of Medical Physics, IEO European Institute of Oncology, IRCCS, Milano, Italy.
Mattia ZaffaroniDivision of Radiation Oncology, IEO European Institute of Oncology, IRCCS, Milano, Italy.
Giulia MarvasoDivision of Radiation Oncology, IEO European Institute of Oncology, IRCCS, Milano, Italy.
Daniela AlterioDivision of Radiation Oncology, IEO European Institute of Oncology, IRCCS, Milano, Italy.
Andrea VavassoriDivision of Radiation Oncology, IEO European Institute of Oncology, IRCCS, Milano, Italy.
Stefano DuranteDivision of Radiation Oncology, IEO European Institute of Oncology, IRCCS, Milano, Italy.
Stefania VolpeDivision of Radiation Oncology, IEO European Institute of Oncology, IRCCS, Milano, Italy.
Federica CattaniDivision of Radiation Oncology, IEO European Institute of Oncology, IRCCS, Milano, Italy.
Barbara Alicja Jereczek-FossaDivision of Radiation Oncology, IEO European Institute of Oncology, IRCCS, Milano, Italy.
Davide MoscatelliDepartment of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano, Piazza Leonardo da Vinci, 32, 20133, Milano, Italy.
Bianca Maria ColosimoDepartment of Mechanical Engineering, Politecnico di Milano, Via La Masa, 1, 20156, Milano, Italy. biancamaria.colosimo@polimi.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The work investigates the implementation of personalized radiotherapy boluses by means of additive manufacturing technologies. Boluses materials that are currently used need an excessive amount of human intervention which leads to reduced repeatability in terms of dosimetry. Additive manufacturing can solve this problem by eliminating the human factor in the process of fabrication. Planar boluses with fixed geometry and personalized boluses printed starting from a computed tomography scan of a radiotherapy phantom were produced. First, a dosimetric characterization study on planar bolus designs to quantify the effects of print parameters such as infill density and geometry on the radiation beam was made. Secondly, a volumetric quantification of air gap between the bolus and the skin of the patient as well as dosimetric analyses were performed. The optimization process according to the obtained dosimetric and airgap results allowed us to find a combination of parameters to have the 3D-printed bolus performing similarly to that in conventional use. These preliminary results confirm those in the relevant literature, with 3D-printed boluses showing a dosimetric performance similar to conventional boluses with the additional advantage of being perfectly conformed to the patient geometry.

Indexed as

Phantoms, ImagingPrinting, Three-DimensionalRadiometryAirHumansRadiotherapyRadiotherapy DosageTomography, X-Ray Computed3D printingAdditive manufacturingBolusRadiotherapy

Identifiers

PMID38351260
PMCPMC11128404

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.