Evidence map›Paper›PMID 38350999›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2024

Upregulated GIRK2 Counteracts Ethanol-Induced Changes in Excitability and Respiration in Human Neurons.

Iya Prytkova, Yiyuan Liu, Michael Fernando, Isabel Gameiro-Ros, Dina Popova, Chella Kamarajan, Xiaoling Xuei, David B Chorlian, Howard J Edenberg, Jay A Tischfield and 5 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Iya PrytkovaNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York 10029.ORCID 0000-0001-8919-8778
Yiyuan LiuDepartment of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029.
Michael FernandoNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York 10029.
Isabel Gameiro-RosNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York 10029.
Dina PopovaHuman Genetics Institute, Rutgers University, Piscataway, New Jersey 08854.
Chella KamarajanDepartment of Psychiatry & Behavioral Sciences, SUNY Downstate Health Sciences University, Brooklyn, New York 11203.
Xiaoling XueiDepartments of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana 46202.
David B ChorlianDepartment of Psychiatry & Behavioral Sciences, SUNY Downstate Health Sciences University, Brooklyn, New York 11203.
Howard J EdenbergDepartments of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana 46202.
Jay A TischfieldHuman Genetics Institute, Rutgers University, Piscataway, New Jersey 08854.
Bernice PorjeszDepartment of Psychiatry & Behavioral Sciences, SUNY Downstate Health Sciences University, Brooklyn, New York 11203.
Zhiping P PangHuman Genetics Institute, Rutgers University, Piscataway, New Jersey 08854.ORCID 0000-0002-6183-1233
Ronald P HartHuman Genetics Institute, Rutgers University, Piscataway, New Jersey 08854.ORCID 0000-0003-4836-8712
Alison GoateNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York 10029 paul.slesinger@mssm.edu alison.goate@mssm.edu.
Paul A SlesingerNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York 10029 paul.slesinger@mssm.edu alison.goate@mssm.edu.ORCID 0000-0002-3868-7528
Icahn School of Medicine at Mount Sinai · USRutgers, The State University of New Jersey · USSUNY Downstate Health Sciences University · USIndiana University School of MedicineRutgers Sexual and Reproductive Health and Rights · NL

Funding

Subject CollectionU10AA008401 · NIAAA · SUNY DOWNSTATE MEDICAL CENTER · PI JAY Arnold TISCHFIELD · 1989 to 2026
$162.7M
COVID and Translational Science supercomputer (CATS)S10OD030463 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2021 to 2021
$2.0M
Big Omics Data Engine 2 SupercomputerS10OD026880 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2019 to 2019
$2.0M
Elucidating the Role of KCNJ6 in a Human Neuronal Model of Alcohol Use DisorderF31AA027949 · NIAAA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI PRYTKOVA, IYA · 2019 to 2021
$132k
NIAAA NIH HHS F31 AA027949NIAAA NIH HHS U10 AA008401NIH HHS S10 OD026880NIH HHS S10 OD030463
6 · The paper itself

Abstract

Genome-wide association studies (GWAS) of electroencephalographic endophenotypes for alcohol use disorder (AUD) has identified noncoding polymorphisms within the

Indexed as

EthanolG Protein-Coupled Inwardly-Rectifying Potassium ChannelsFemaleGenome-Wide Association StudyHumansMaleNeuronsRespirationEthanolG Protein-Coupled Inwardly-Rectifying Potassium ChannelsalcoholCRISPRaexcitabilityglutamateKCNJ6mitochondria

Identifiers

PMID38350999
PMCPMC11026340
OpenAlexW4391773542

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.