ArticleBMC oral health2024
Platelet rich fibrin and MTA in the treatment of teeth with open apices.
Article in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
5 citing papers in PubMed, 4 citations in OpenAlex.
- Orthograde Apical Barrier in Non-Vital Immature Permanent Teeth: A Narrative Review of Clinical Pathways, Procedural Determinants, and Evidence Gaps.Dentistry journal · 2026Review
- A Comparative Study of Platelet-Rich Fibrin (PRF) and Titanium-Prepared Platelet-Rich Fibrin (T-PRF) in Management of Endo-Perio Lesion.Journal of pharmacy & bioallied sciences · 2024Article
- Concentrated Growth Factors for Managing a Nonvital Maxillary Central Incisor With an Open Apex.Cureus · 2024Article
- Correction: Platelet rich fibrin and MTA in the treatment of teeth with open apices.BMC oral health · 2024Article
- Article
Corrections and comments
- Erratum issued
Authors and funding
17 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe present study aimed to evaluate the effectiveness of using platelet-rich fibrin (PRF) as the apical matrix for the placement of MTA in nonsurgical endodontic therapy for teeth with periapical lesions and open apices.
methodsTwelve teeth from eleven patients with periapical periodontitis and open apices were enrolled in the study. Nonsurgical endodontic therapy was performed with the PRF used as an apical barrier and the MTA manipulated as an apical plug for further thermoplasticized gutta percha in the remaining part of the root canal. Clinical signs and periapical digital radiographs were recorded and analyzed to evaluate the curing progress after periodical follow-ups of 1, 3, and 6 months. The horizontal dimension of the periapical lesion was determined, and the changes in the dimensions were recorded each time. The Friedman test was used for statistical analysis, with P < .05 serving as the threshold for determining statistical significance.
resultsAll patients had no clinical symptoms after the first month of treatment, with a significant reduction in the periapical lesion after periodical appointments.
conclusionsPRF is an effective barrier when combined with MTA for the treatment of teeth with periapical periodontitis and open apices.
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Registered trials
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