Evidence map›Paper›PMID 38350849›Full record

SynthesisBMC cardiovascular disorders2024

Effect of mindfulness-based interventions on people with prehypertension or hypertension: a systematic review and meta-analysis of randomized controlled trials.

Qiongshan Chen, Hui Liu, Shizheng Du

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC cardiovascular disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06756477 (The Effect of Mindfulness-Based Healthy Living Behaviors Training on Premenstrual Syndrome Symptoms and Quality of Life), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
11.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06756477 nacompletednot on this mapstarted 2025, after this paper: background citation

The Effect of Mindfulness-Based Healthy Living Behaviors Training on Premenstrual Syndrome Symptoms and Quality of Life

TypeinterventionalSponsorNisan AkçayRan2025 to 2025Enrolled114ConditionsMindfulness, Premenstrual Syndrome-PMS, Quality of LifeArmsmindfulness group, control group
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Review
  5. The Japanese Society of Hypertension Guidelines for the management of elevated blood pressure and hypertension 2025 (JSH2025).Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Additional Non-Pharmacological Intervention for Elderly Patients With Hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2025
    Article
  10. Review
  11. Article
  12. Meta-Analytic Insights Into Mindfulness Approaches for Depression and Diabetes Comorbidity Care.Diabetes spectrum : a publication of the American Diabetes Association · 2025
    Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Qiongshan ChenShantou University Medical College, 22 Xinling Road, Jinping District, Shantou, Guangdong Province, 515041, China.
Hui LiuDepartment of Cardiology, The Second Affiliated Hospital of Shantou University Medical College, 69 Dongxia Road, Jinping District, Shantou, Guangdong Province, 515041, China. hexu832003@163.com.
Shizheng DuSchool of Nursing, Nanjing University of Chinese Medicine, 138 Xianlin Avenue, Qixia District, Nanjing, Jiangsu Province, 210023, China.
Nanjing University of Chinese Medicine · CNSecond Affiliated Hospital of Shantou University Medical College · CNShantou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypertension and prehypertension have been widely recognized as the main contributors of global mortality. Evidence shows mindfulness-based interventions may reduce blood pressure and improve mental health. However, the effect of mindfulness-based interventions on blood pressure and mental health has not been fully understood.

methodsPotential studies published before May 24th 2023 were identified by searching Embase, Ovid Emcare, PsycINFO, CINAHL, Web of Science, Cochrane, PubMed, China National Knowledge Infrastructure, Wanfang database, and VIP China Science. Additionally, two grey databases were searched: Mednar, WorldWideScience.org. The risk of bias in the included studies was assessed using the Cochrane Risk of Bias Assessment tool. The random-effects meta-analyses were conducted using Review Man 5.4 software and the key outcomes are presented as mean difference or standard mean difference and the 95% confidential interval.

resultsSearches returned 802 studies in total, of which 12 were included (N = 715). The duration of interventions was 8 weeks in 10 trials and 6 weeks in one trial. Pooled effect sizes indicated reductions in systolic blood pressure (MD = - 9.12, 95% CI [- 12.18, - 6.05], p < 0.001), diastolic blood pressure (MD = - 5.66, 95% CI [- 8.88, - 2.43], p < 0.001), anxiety (SMD = - 4.10; 95% CI [- 6.49, - 1.71], p < 0.001), depression (SMD = - 1.70, 95%CI [- 2.95, - 0.44], p < 0.001) and perceived stress (SMD = - 5.91, 95%CI [- 8.74, - 3.09], p < 0.001) at post-intervention. The findings from subgroup analyses are favorable for mindfulness-based interventions regardless of gender and baseline blood pressure with regard to BP reduction, with a more profound effect observed in participants with higher pre-intervention blood pressure.

conclusionsThe results provide evidence for the positive role of mindfulness-based interventions in hypertension management. More large randomized control trials with sufficient statistical power and long-term follow-up are needed.

trial registrationThe protocol had been registered with Prospero on October 2nd 2021 (registration NO. CRD42021282504 ).

Indexed as

Blood PressureHypertensionMental HealthMindfulnessPrehypertensionRandomized Controlled Trials as TopicAdultAgedFemaleHumansMaleMiddle AgedTreatment OutcomeAnxietyBlood pressureDepressionHypertensionMindfulness

Identifiers

PMID38350849
PMCPMC10865530
OpenAlexW4391819568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.