Evidence map›Paper›PMID 38350611›Full record

ArticleOpen biology2024

miR-1202 acts as anti-oncomiR in myeloid leukaemia by down-modulating GATA-1

Raffaele Sessa, Silvia Trombetti, Alessandra Lo Bianco, Giovanni Amendola, Rosa Catapano, Elena Cesaro, Fara Petruzziello, Maria D'Armiento, Giuseppe Maria Maruotti, Giuseppe Menna and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Raffaele SessaDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy.ORCID 0000-0003-4835-357X
Silvia TrombettiDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy.
Alessandra Lo BiancoDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy.
Giovanni AmendolaDepartment of Pediatrics and Intensive Care Unit, Umberto I Hospital, Nocera Inferiore, Italy.
Rosa CatapanoDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy.
Elena CesaroDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy.ORCID 0000-0003-3931-7956
Fara PetruzzielloDepartment of Pediatric Hemato-Oncology, AORN Santobono-Pausilipon, Naples, Italy.
Maria D'ArmientoDepartment of Public Health, Section of Pathology, University of Naples Federico II, Naples, Italy.
Giuseppe Maria MaruottiGynecology and Obstetrics Unit, Department of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Naples, Italy.
Giuseppe MennaDepartment of Pediatric Hemato-Oncology, AORN Santobono-Pausilipon, Naples, Italy.
Paola IzzoDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy.
Michela GrossoDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy.ORCID 0000-0003-1664-1657
University of Naples Federico II · ITCeinge Biotecnologie Avanzate (Italy) · ITFederico II University Hospital · ITPoliclinico Umberto I · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transient abnormal myelopoiesis (TAM) is a Down syndrome-related pre-leukaemic condition characterized by somatic mutations in the haematopoietic transcription factor GATA-1 that result in exclusive production of its shorter isoform (GATA-1

Indexed as

Down SyndromeLeukemia, MyeloidLeukemoid ReactionMicroRNAsGATA1 Transcription FactorHumansGATA1 protein, humanGATA1 Transcription FactorMicroRNAsMIRN1202 microRNA, humanalternative splicingDown syndromeGATA-1miR-1202myeloid leukaemia

Identifiers

PMID38350611
PMCPMC10864098
OpenAlexW4392786893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.