Evidence map›Paper›PMID 38350494›Full record

Trial reportArchives of physical medicine and rehabilitation2024

An 8-week Forced-rate Aerobic Cycling Program Improves Cardiorespiratory Fitness in Persons With Chronic Stroke: A Randomized Controlled Trial.

Susan M Linder, John Lee, Francois Bethoux, Daniel Persson, Andrea Bischof-Bockbrader, Sara Davidson, Yadi Li, Brittany Lapin, Julie Roberts, Alexandra Troha and 3 more

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Archives of physical medicine and rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Susan M LinderCleveland Clinic, Department of Physical Medicine and Rehabilitation, Cleveland, OH; Cleveland Clinic, Department of Biomedical Engineering, Lerner Research Institute, Cleveland, OH. Electronic address: linders@ccf.org.
John LeeCleveland Clinic, Department of Physical Medicine and Rehabilitation, Cleveland, OH.
Francois BethouxCleveland Clinic, Department of Physical Medicine and Rehabilitation, Cleveland, OH.
Daniel PerssonOhio University Heritage College of Osteopathic Medicine, Athens, OH.
Andrea Bischof-BockbraderCleveland Clinic, Department of Physical Medicine and Rehabilitation, Cleveland, OH.
Sara DavidsonCleveland Clinic, Concussion Center, Neurologic Institute, Cleveland, OH.
Yadi LiCleveland Clinic, Department of Quantitative Health Sciences, Lerner Research Institute, Cleveland, OH; Cleveland Clinic, Center for Outcomes Research and Evaluation, Neurological Institute, Cleveland, OH.
Brittany LapinCleveland Clinic, Department of Quantitative Health Sciences, Lerner Research Institute, Cleveland, OH; Cleveland Clinic, Center for Outcomes Research and Evaluation, Neurological Institute, Cleveland, OH.
Julie RobertsCleveland Clinic, Department of Cardiovascular Medicine; Heart, Vascular, and Thoracic Institute, Cleveland, OH.
Alexandra TrohaCleveland Clinic, Department of Cardiovascular Medicine; Heart, Vascular, and Thoracic Institute, Cleveland, OH.
Logan MaagCleveland Clinic, Department of Physical Medicine and Rehabilitation, Cleveland, OH.
Tamanna SinghCleveland Clinic, Department of Cardiovascular Medicine; Heart, Vascular, and Thoracic Institute, Cleveland, OH.
Jay L AlbertsCleveland Clinic, Department of Biomedical Engineering, Lerner Research Institute, Cleveland, OH; Cleveland Clinic, Concussion Center, Neurologic Institute, Cleveland, OH.
Cleveland Clinic · USOhio University · US

Funding

Cost-effectiveness and efficacy of a combined intervention to facilitate motor recovery following strokeK01HD092556 · NICHD · CLEVELAND CLINIC LERNER COM-CWRU · PI LINDER, SUSAN MARIE · 2018 to 2022
$666k
NICHD NIH HHS K01 HD092556
6 · The paper itself

Abstract

objectiveTo examine the cardiorespiratory effects of a forced-rate aerobic exercise (FE) intervention among individuals with chronic stroke compared with an upper extremity repetitive task practice (UE RTP) control group.

designSecondary analysis of data from a randomized controlled trial.

settingResearch laboratory.

participantsIndividuals with chronic stroke (N=60).

interventionsParticipants completed 24 sessions of FE followed by RTP (FE+RTP, N=30) or time matched RTP alone (N=30). The FE+RTP group was prescribed exercise at 60%-80% of heart rate reserve on a motorized stationary cycle ergometer for 45 minutes followed by 45 minutes of RTP. The control group completed 90 minutes of RTP.

main outcome measuresMetabolic exercise stress tests on a cycle ergometer were conducted at baseline and post-intervention. Outcomes included peak oxygen consumption (peak V̇o

resultsFifty participants completed the study intervention and pre/post stress tests. The FE+RTP group demonstrated significantly greater improvements in peak V̇o

conclusionsWhile the aerobic exercise intervention was integrated into rehabilitation to improve UE motor recovery, it was also effective in eliciting significant and meaningful improvements in cardiorespiratory fitness. This novel rehabilitation model may be an effective approach to improve motor and cardiorespiratory function in persons recovering from stroke.

Indexed as

Cardiorespiratory FitnessExercise TherapyOxygen ConsumptionStroke RehabilitationAgedAnaerobic ThresholdBicyclingChronic DiseaseExercise TestFemaleHumansMaleMiddle AgedStrokeAerobic exerciseCardiopulmonary exercise testCardiorespiratory fitnessRehabilitation

Identifiers

PMID38350494
PMCPMC11069437
OpenAlexW4391735417

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.