Evidence map›Paper›PMID 38350301›Full record

SynthesisThe journal of nutrition, health & aging2024

The effect of stroke on the bone mineral density: A systematic review and meta-analysis.

Jun Wang, Yanshan Sun, Xiang Guo, Zhen Zhang, Hanguang Liang, Tong Zhang

Open access · goldAbstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in The journal of nutrition, health & aging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Identifying risk factors for systemic complications following fracture-related infection.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Article
  6. Article
  7. Article
  8. Bone health post-stroke: a survey of stroke care physiatrists in Canada.Journal of rehabilitation medicine. Clinical communications · 2025
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Jun WangSchool of Rehabilitation Medicine, Capital Medical University, Beijing, 100069, China; Lab of Brain Injury Repair and Rehabilitation, China Rehabilitation Science Institute, Beijing 100068, China; Neurological Rehabilitation, Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing, 100077, China. Electronic address: abcd2878@126.com.
Yanshan SunDepartment of Joint Surgery, Weifang People's Hospital, Weifang, Shandong, 261041, China.
Xiang GuoDepartment of Spine Surgery, Affiliated Hospital of Weifang Medical University, Weifang, Shandong, 261041, China.
Zhen ZhangDepartment of Joint Surgery, Weifang People's Hospital, Weifang, Shandong, 261041, China.
Hanguang LiangDepartment of Joint Surgery, Weifang People's Hospital, Weifang, Shandong, 261041, China.
Tong ZhangSchool of Rehabilitation Medicine, Capital Medical University, Beijing, 100069, China; Lab of Brain Injury Repair and Rehabilitation, China Rehabilitation Science Institute, Beijing 100068, China; Neurological Rehabilitation, Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing, 100077, China. Electronic address: tom611@126.com.
Weifang People's Hospital · CNCapital Medical University · CNChina Rehabilitation Research Center · CNWeifang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesStroke survivors frequently encounter physical complications. This study aimed to evaluate the impact of stroke on bone mineral density (BMD) and assess the risk of post-stroke osteoporosis or osteoporotic fractures.

designSystematic review and meta-analysis. SETTING AND

participantsWe systematically searched Medline, Embase, and the Cochrane Database of Systematic Reviews to identify longitudinal studies reporting the influence of stroke on BMD, osteoporosis, and osteoporotic fractures. Pooled analyses were performed utilizing random-effects models.

resultsThis study included 21 studies with 1,029,742 participants. The mean difference of BMD in the paretic femoral neck between follow-up and initial measurements was -0.07 g/cm

conclusionStroke survivors undergo significant BMD loss in paralyzed limbs, most notably in the femoral neck. However, BMD in the lumbar spine does not exhibit a significant decrease post-stroke. The risk of post-stroke osteoporosis or osteoporotic fractures should be interpreted with caution and needs further investigation.

Indexed as

Bone DensityOsteoporosisOsteoporotic FracturesStrokeAgedFemaleFemur NeckHumansMaleBone densityHemiplegiaOsteoporosisOsteoporotic fractureStroke

Identifiers

PMID38350301
PMCPMC12877220
OpenAlexW4391764936

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.