Evidence map›Paper›PMID 38349882›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

YfmR is a translation factor that prevents ribosome stalling and cell death in the absence of EF-P.

Hye-Rim Hong, Cassidy R Prince, Daniel D Tetreault, Letian Wu, Heather A Feaga

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 27 citations in OpenAlex.

  1. Translation factors that keep the ribosome Pro-active.Microbiology and molecular biology reviews : MMBR · 2026
    Review
  2. Collided ribosomes are rescued by the endonuclease Rae1 andbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Pleiotropic roles of elongation factor P inMicrobiology spectrum · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Structural Basis of TACO1-Mediated Efficient Mitochondrial Translation.bioRxiv : the preprint server for biology · 2025
    Article
  12. Article
  13. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hye-Rim HongDepartment of Microbiology, Cornell University, Ithaca, NY 14853.ORCID 0000-0002-8339-3190
Cassidy R PrinceDepartment of Microbiology, Cornell University, Ithaca, NY 14853.ORCID 0000-0003-2740-522X
Daniel D TetreaultDepartment of Microbiology, Cornell University, Ithaca, NY 14853.ORCID 0000-0002-3043-5852
Letian WuDepartment of Microbiology, Cornell University, Ithaca, NY 14853.ORCID 0009-0005-9029-3840
Heather A FeagaDepartment of Microbiology, Cornell University, Ithaca, NY 14853.ORCID 0009-0007-3190-5135
Cornell University · US

Funding

Ribosome Quality Control Mechanisms in Gram-Positive BacteriaR35GM147049 · NIGMS · CORNELL UNIVERSITY · PI Heather Feaga · 2022 to 2026
$1.9M
NIGMS NIH HHS R35 GM147049
6 · The paper itself

Abstract

Protein synthesis is performed by the ribosome and a host of highly conserved elongation factors. Elongation factor P (EF-P) prevents ribosome stalling at difficult-to-translate sequences, such as polyproline tracts. In bacteria, phenotypes associated with

Indexed as

Escherichia coliEscherichia coli ProteinsATP-Binding Cassette TransportersCell DeathPeptide Elongation FactorsProtein BiosynthesisRibosomesATP-Binding Cassette TransportersEscherichia coli ProteinsEttA protein, E colifactor EF-PPeptide Elongation FactorsUup protein, E coliABCFbacteriaEF-Pribosometranslation

Identifiers

PMID38349882
PMCPMC10895253
OpenAlexW4391774036

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.