Evidence map›Paper›PMID 38349582›Full record

ArticleInternational ophthalmology2024

Long-term ocular surface stability in conjunctivolimbal autograft and ocular surface safety in the donor eyes.

Burcu Nurozler Tabakci, Ayşe Burcu, Züleyha Yalnız Akkaya, Evin Şıngar, Selma Ozbek-Uzman, Firdevs Örnek

Abstract read
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In one paragraph

Article in International ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Burcu Nurozler TabakciOphthalmology Department, Basaksehir Cam and Sakura City Hospital, Basaksehir, Istanbul, Turkey. burcunurtabakci@gmail.com.ORCID http://orcid.org/0000-0001-8893-1739
Ayşe BurcuOphthalmology Department, University of Health Sciences Ankara Training and Research Hospital, Ankara, Turkey.ORCID http://orcid.org/0000-0002-2345-0456
Züleyha Yalnız AkkayaOphthalmology Department, University of Health Sciences Ankara Training and Research Hospital, Ankara, Turkey.ORCID http://orcid.org/0000-0003-3817-2214
Evin ŞıngarOphthalmology Department, University of Health Sciences Ankara Training and Research Hospital, Ankara, Turkey.ORCID http://orcid.org/0000-0002-8452-8595
Selma Ozbek-UzmanOphthalmology Department, University of Health Sciences Ankara Training and Research Hospital, Ankara, Turkey.ORCID http://orcid.org/0000-0002-4967-7325
Firdevs ÖrnekOphthalmology Department, University of Health Sciences Ankara Training and Research Hospital, Ankara, Turkey.ORCID http://orcid.org/0000-0003-2412-0675
Ministry of Health · TREskişehir City Hospital · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe current study is aimed to present the long-term results of the patients who underwent conjunctivolimbal autograft (CLAU) as the primary operation in unilateral limbal stem cell deficiency and the ocular surface safety of the donor eyes. The patients were followed up for five years or longer.

methodsThe records of all patients who underwent CLAU as the primary operation were retrospectively analyzed. Additional ocular surface operations, ocular surface stability, best-corrected visual acuity (BCVA), and ocular surface status of the donor eyes were investigated.

resultsThe mean age of the patients at the time of transplantation was 35.07 ± 12.9 (12-60). Twenty-nine eyes of 29 patients were followed up for an average of 97.82 ± 34.45 (60-186) months. Additional ocular surface operation was required in 27.58% (8/29) of the eyes in order to achieve a stable ocular surface. Ocular surface stability was achieved in 82.75% (24/29) of the eyes at the end of the follow-up period. BCVA increased from 1.78 ± 0.82 to 0.91 ± 0.92 logMAR at the last visit (p < 0.001). Corneal ectasia and vascularization developed in one donor eye in the fifth postoperative year.

conclusionsCLAU tissues provide ocular surface stability with a successful vision result in the long term. CLAU theoretically carries risks including limbal stem cell deficiency in the donor eye. In the long-term follow-up of donor eyes after CLAU, ectasia and limbal stem cell deficiency were observed in one eye.

Indexed as

Limbal Stem Cell DeficiencyAutograftsDilatation, PathologicEyeHumansRetrospective StudiesConjunctivolimbal autograftDonor eyeEctasiaLimbal stem cell deficiencyOcular surface

Identifiers

PMID38349582
OpenAlexW4391779763

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.