ReviewArchives of microbiology2024
Mechanisms of antifungal resistance and developments in alternative strategies to combat Candida albicans infection.
Review in Archives of microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 18 citations in OpenAlex.
- Disulfiram reverses fluconazole-resistance mediated by Cdr1 in Candida albicans and interferes with biofilm formation.Applied microbiology and biotechnology · 2026Article
- Modulating the amphiphilic character of porphyrins with pH-activatable cationic centers and fluorocarbon chains to enhance antimicrobial photodynamic activity against Candida albicans.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026Article
- Curcumin-mediated antimicrobial photodynamic therapy prevents Candida biofilm formation in a species-dependent manner.Lasers in medical science · 2026Article
- Comparison of some biological activities of essential oils and extracts (waste and non-waste) of two species used by people: Salvia macrosiphon Boiss. and Salvia reuteriana Boiss. from natural habitats of Kashan.BMC plant biology · 2026Article
- Atractylodin Enhances the Efficacy of Fluconazole Against Fluconazole-Resistant C. albicans by Promoting ROS Accumulation and Synergizes with Fluconazole Against C. albicans Biofilm.Mycopathologia · 2026Article
- Antifungal activity of gold nanoparticles synthesized by laser ablation with blue diode laser photodynamic activation against Candida albicans.Lasers in medical science · 2026Article
- Article
- The roles ofFrontiers in medicine · 2026Article
- Antimicrobial efficacy and cytotoxic assessment of plasma-activated water generated by a dielectric barrier discharge microbubble system.Frontiers in microbiology · 2026Article
- Antifungal effects and potential mechanism of bortezomib in combination with fluconazole againstFrontiers in cellular and infection microbiology · 2026Article
- Mechanism of action of quinoline-based ionic liquids against the pathogenesis of the fungal pathogen, Candida albicans.Journal of biosciences · 2026Article
- Ripening-Related Changes in Color and Bioactive Compounds ofFoods (Basel, Switzerland) · 2025Article
- Double-Layer Magnetic Microspheres with Dual Drug Delivery of Antibacterial and Maintenance Agents for the Treatment ofACS omega · 2025Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Candida albicans is a commensal fungus that infects the humans and becomes an opportunistic pathogen particularly in immuno-compromised patients. Among the Candida genus, yeast C. albicans is the most frequently incriminated species and is responsible for nearly 50-90% of human candidiasis, with vulvovaginal candidiasis alone, affecting about 75% of the women worldwide. One of the significant virulence traits in C. albicans is its tendency to alternate between the yeast and hyphae morphotypes, accounting for the development of multi-drug resistance in them. Thus, a thorough comprehension of the decision points and genes controlling this transition is necessary, to understand the pathogenicity of this, naturally occurring, pernicious fungus. Additionally, the formation of C. albicans biofilm is yet another pathogenesis trait and a paramount cause of invasive candidiasis. Since 1980 and in 90 s, wide spread use of immune-suppressing therapies and over prescription of fluconazole, a drug used to treat chronic fungal infections, triggered the emergence of novel anti-fungal drug development. Thus, this review thoroughly elucidates the diseases associated with C. albicans infection as well as the anti-fungal resistance mechanism associated with them and identifies the emerging therapeutic agents, along with a rigorous discussion regarding the future strategies that can possibly be adopted for the cure of this deleterious pathogen.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.