Evidence map›Paper›PMID 38349508›Full record

Observational studyEuropean geriatric medicine2024

Preoperative frailty predicts postoperative pain after total knee arthroplasty in older patients: a prospective observational study.

Yinan Jin, Suhong Tang, Wenwen Wang, Wei Zhang, Yunfan Hou, Yang Jiao, Bailing Hou, Zhengliang Ma

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in European geriatric medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
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  7. Reply to the letter by Guoying Wang.Journal of anesthesia · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yinan Jin *Department of Anesthesiology, Affiliated Drum Tower Hospital, Medical School, Nanjing University, 321 Zhongshan Road, Nanjing, 210008, China.
Suhong Tang *Department of Anesthesiology, Affiliated Drum Tower Hospital, Medical School, Nanjing University, 321 Zhongshan Road, Nanjing, 210008, China.
Wenwen Wang *Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China.
Wei ZhangDepartment of Anesthesiology, Affiliated Drum Tower Hospital, Medical School, Nanjing University, 321 Zhongshan Road, Nanjing, 210008, China.
Yunfan HouDepartment of Anesthesiology, Affiliated Drum Tower Hospital, Medical School, Nanjing University, 321 Zhongshan Road, Nanjing, 210008, China.
Yang JiaoDepartment of Anesthesiology, Affiliated Drum Tower Hospital, Medical School, Nanjing University, 321 Zhongshan Road, Nanjing, 210008, China. 15026967597@163.com.
Bailing HouDepartment of Anesthesiology, Affiliated Drum Tower Hospital, Medical School, Nanjing University, 321 Zhongshan Road, Nanjing, 210008, China. houbailing1989@163.com.
Zhengliang MaDepartment of Anesthesiology, Affiliated Drum Tower Hospital, Medical School, Nanjing University, 321 Zhongshan Road, Nanjing, 210008, China. mazhengliang1964@nju.edu.cn.

Funding

Key Technologies Research and Development Program 2018YFC2001800National Natural Science Foundation of China 81971044
6 · The paper itself

Abstract

purposeFrailty is reportedly associated with postoperative adverse outcomes and may increase the risk of post-surgical pain. Our study aimed to explore whether frailty was an independent risk factor for pain after total knee arthroplasty (TKA) in older patients.

methodsIncluded in this prospective observational study were patients aged 65 or older who underwent primary TKA. Frailty of the patients was assessed before surgery using the comprehensive geriatric assessment-frailty index and pain was evaluated before and after surgery using the Numerical Rating Scale.

resultsOf the 164 patients including 125 females with a mean age of 71.4 ± 4.6 years, 51 patients were identified as being frail. Patients with chronic post-surgical pain had a significantly higher frailty index than those without chronic post-surgical pain, which was the same in patients with acute post-surgical pain. After adjusting for other confounding factors, frailty was shown to be an independent risk factor for both acute (OR: 13.23, 95% CI 3.73-46.93, P < 0.001) and chronic post-surgical pain (OR: 4.24, 95% CI 1.29-14.00, P = 0.02). The area under the receiver operating characteristic curve for frailty predicting chronic post-surgical pain was 0.73 (P < 0.001, 95% CI 0.65-0.81).

conclusionsOur findings demonstrated that preoperative frailty in older patients was a predictor of acute and chronic post-surgical pain after TKA, suggesting that frailty assessment should become a necessary procedure before operations, especially in older patients.

Indexed as

Arthroplasty, Replacement, KneeFrailtyPostoperative PainAgedAged, 80 and overFemaleFrail ElderlyGeriatric AssessmentHumansMalePain MeasurementPreoperative PeriodProspective StudiesRisk FactorsROC CurveAcute post-surgical pain (APSP)Chronic post-surgical pain (CPSP)FrailtyTotal knee arthroplasty (TKA)

Identifiers

PMID38349508

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.