Evidence map›Paper›PMID 38349130›Full record

ArticlemBio2024

Batf3-dependent orchestration of the robust Th1 responses and fungal control during cryptococcal infection, the role of cDC1.

Jintao Xu, Rylan Hissong, Rachel Bareis, Arianna Creech, Kristie D Goughenour, Christine M Freeman, Michal A Olszewski

Open access · goldAbstract read
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Foxp3Research square · 2025
    Article
  9. Article
  10. Fungal immunization potentiates CD4Frontiers in immunology · 2025
    Article
  11. Review
  12. Review
  13. Inbred Mouse Models inJournal of fungi (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jintao XuResearch Service, Department of Veterans Affairs Health System, Ann Arbor VA Health System, Ann Arbor, Michigan, USA.ORCID 0000-0002-9946-8601
Rylan HissongResearch Service, Department of Veterans Affairs Health System, Ann Arbor VA Health System, Ann Arbor, Michigan, USA.
Rachel BareisResearch Service, Department of Veterans Affairs Health System, Ann Arbor VA Health System, Ann Arbor, Michigan, USA.
Arianna CreechResearch Service, Department of Veterans Affairs Health System, Ann Arbor VA Health System, Ann Arbor, Michigan, USA.
Kristie D GoughenourResearch Service, Department of Veterans Affairs Health System, Ann Arbor VA Health System, Ann Arbor, Michigan, USA.
Christine M FreemanResearch Service, Department of Veterans Affairs Health System, Ann Arbor VA Health System, Ann Arbor, Michigan, USA.
Michal A OlszewskiResearch Service, Department of Veterans Affairs Health System, Ann Arbor VA Health System, Ann Arbor, Michigan, USA.ORCID 0000-0001-7474-0843
Michigan Medicine · US

Funding

PULMONARY CELLULAR AND MOLECULAR BIOLOGY TRAININGT32HL007749 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Robert Pickett Dickson · 1993 to 2026
$19.9M
Regulatory T Cell Inhibition of Natural Killer Cells in COPDI01CX001553 · VA · VETERANS HEALTH ADMINISTRATION · PI Christine M Basmajian · 2017 to 2026
–
Offsetting CNS inflammatory damage with anti-CXCR3 antibody immunotherapyI21BX006349 · VA · VETERANS HEALTH ADMINISTRATION · PI OLSZEWSKI, MICHAL A · 2024 to 2025
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Modulation of Pulmonary Defenses in Pathobiology of Chronic InfectionsI01BX000656 · VA · VETERANS HEALTH ADMINISTRATION · PI OLSZEWSKI, MICHAL A · 2011 to 2025
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BLR&D Research Career Scientist Award ApplicationIK6BX003615 · VA · VETERANS HEALTH ADMINISTRATION · PI OLSZEWSKI, MICHAL A · 2017 to 2021
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BLRD Research Career Scientist Award ApplicationIK6BX005966 · VA · VETERANS HEALTH ADMINISTRATION · PI OLSZEWSKI, MICHAL A · 2022 to 2025
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Mechanism of cryptococcal fitness, innate defense subversion, and the adaptive immune skewing in lungsIK2BX006208 · VA · VETERANS HEALTH ADMINISTRATION · PI GOUGHENOUR, KRISTIE D · 2023 to 2025
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BLRD VA I01 BX000656BLRD VA I21 BX006349BLRD VA IK2 BX006208BLRD VA IK6 BX003615BLRD VA IK6 BX005966CSRD VA I01 CX001553NHLBI NIH HHS T32 HL007749
6 · The paper itself

Abstract

While type I conventional dendritic cells (cDC1s) are vital for generating adaptive immunity against intracellular pathogens and tumors, their role in defense against fungal pathogen

Indexed as

CryptococcosisCryptococcus neoformansMeningoencephalitisAnimalsBasic-Leucine Zipper Transcription FactorsCD4-Positive T-LymphocytesDendritic CellsImmunity, CellularMiceRepressor ProteinsBasic-Leucine Zipper Transcription FactorsRepressor ProteinsSNFT protein, mouseBatf3cDC1cryptococcal infectiondendritic cellsfungal infectionTh1 responses

Identifiers

PMID38349130
PMCPMC10936214
OpenAlexW4391786653

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.