Evidence map›Paper›PMID 38348822›Full record

ArticleAnalytical chemistry2024

Bringing to Light the Importance of the miRNA Methylome in Colorectal Cancer Prognosis Through Electrochemical Bioplatforms.

Eloy Povedano, Víctor Ruiz-Valdepeñas Montiel, Ravery Sebuyoya, Rebeca M Torrente-Rodríguez, Maria Garranzo-Asensio, Ana Montero-Calle, José M Pingarrón, Rodrigo Barderas, Martin Bartosik, Susana Campuzano

Open access · hybridAbstract read
In one paragraph

Article in Analytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Eloy PovedanoDepartamento de Química Analítica, Facultad de CC. Químicas, Universidad Complutense de Madrid, Pza. de las Ciencias 2, Madrid 28040, Spain.
Víctor Ruiz-Valdepeñas MontielDepartamento de Química Analítica, Facultad de CC. Químicas, Universidad Complutense de Madrid, Pza. de las Ciencias 2, Madrid 28040, Spain.ORCID 0000-0002-8865-1531
Ravery SebuyoyaResearch Centre for Applied Molecular Oncology, Masaryk Memorial Cancer Institute, Zluty kopec 7, Brno 656 53, Czech Republic.
Rebeca M Torrente-RodríguezDepartamento de Química Analítica, Facultad de CC. Químicas, Universidad Complutense de Madrid, Pza. de las Ciencias 2, Madrid 28040, Spain.
Maria Garranzo-AsensioChronic Disease Programme, UFIEC, Institute of Health Carlos III, Majadahonda, Madrid 28220, Spain.
Ana Montero-CalleChronic Disease Programme, UFIEC, Institute of Health Carlos III, Majadahonda, Madrid 28220, Spain.
José M PingarrónDepartamento de Química Analítica, Facultad de CC. Químicas, Universidad Complutense de Madrid, Pza. de las Ciencias 2, Madrid 28040, Spain.ORCID 0000-0003-2271-1383
Rodrigo BarderasChronic Disease Programme, UFIEC, Institute of Health Carlos III, Majadahonda, Madrid 28220, Spain.ORCID 0000-0003-3539-7469
Martin BartosikResearch Centre for Applied Molecular Oncology, Masaryk Memorial Cancer Institute, Zluty kopec 7, Brno 656 53, Czech Republic.
Susana CampuzanoDepartamento de Química Analítica, Facultad de CC. Químicas, Universidad Complutense de Madrid, Pza. de las Ciencias 2, Madrid 28040, Spain.ORCID 0000-0002-9928-6613
Universidad Complutense de Madrid · ESInstituto de Salud Carlos III · ESMasaryk Memorial Cancer Institute · CZMasaryk University · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work reports the first electrochemical bioplatforms developed for the determination of the total contents of either target miRNA or methylated target miRNA. The bioplatforms are based on the hybridization of the target miRNA with a synthetic biotinylated DNA probe, the capture of the formed DNA/miRNA heterohybrids on the surface of magnetic microcarriers, and their recognition with an antibody selective to these heterohybrids or to the

Indexed as

Biosensing TechniquesColorectal NeoplasmsMicroRNAsAntibodiesEpigenomeHumansNucleic Acid HybridizationPrognosisAntibodiesMicroRNAs

Identifiers

PMID38348822
PMCPMC10955513
OpenAlexW4391786467

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.