ArticleJournal of children's orthopaedics2024
As simple as it sounds? The treatment of simple bone cysts in the proximal femur in children and adolescents: Retrospective multicenter EPOS study of 74 patients.
Article in Journal of children's orthopaedics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 8 citations in OpenAlex.
- [Surgical management of juvenile and aneurysmal bone cysts in children and adolescents : Curettage, ceramic bone graft substitution and adjuvants].Operative Orthopadie und Traumatologie · 2026Trial
- Elastic Stable Intramedullary Nailing for High-Risk Proximal Femoral Unicameral Bone Cysts in Children: A Retrospective Case Series.Journal of the Pediatric Orthopaedic Society of North America · 2026Article
- Watchful waiting versus methylprednisolone or polidocanol injections as treatment of simple bone cysts.Bone & joint open · 2026Article
- How the anatomic location affects the surgical outcomes of simple bone cysts in children: a single-center retrospective cohort study.Journal of orthopaedic surgery and research · 2026Article
- The most common bone tumors of the upper extremity in childhood and adolescence and their treatment: a review of the current literature.EFORT open reviews · 2026Review
- Elastic stable intramedullary nailing alone for unicameral bone cysts of the humerus in children: a mid-term follow-up study.Frontiers in pediatrics · 2026Article
- Surgical Technique: Management of a Pathological Fracture in the Femoral Neck: Case Report and Literature Review.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025Review
- Combined curettage, fibular and iliac bone grafting, and dynamic hip screw fixation for a femoral neck simple bone cyst in a child with excellent functional outcome: a case report.Journal of medical case reports · 2025Article
- Surgical treatment of monostotic fibrous dysplasia of the proximal femur in children and adolescents: Observational European Paediatric Orthopaedic Society multicenter study.Journal of children's orthopaedics · 2025Article
- Longitudinal Management of Progressive Femoral Deformities in a Pediatric Patient: A Case Study on Adaptative Surgical Interventions and Outcomes.Journal of orthopaedic case reports · 2025Article
- Surgical treatment of proximal femur unicameral bone cysts in children: a retrospective single-center study.World journal of pediatric surgery · 2025Article
Corrections and comments
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Authors and funding
19 authors at 11 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Simple bone cysts are among the most prevalent benign cystic tumor-like lesions in children. Proximal femoral simple bone cysts may require specific treatment because of increased fracture risk. With limited literature available on this specific localization, consensus regarding optimal treatment is lacking. We present a large international multicenter retrospective cohort study on proximal femoral simple bone cysts. Methods: All consecutive pediatric patients with proximal femoral simple bone cyst from 10 tertiary referral centers for musculoskeletal oncology were included (2000-2021). Demographics, primary treatment, complications, and re-operations were evaluated. Primary outcomes were time until full weight-bearing and failure-free survival. Results: Overall, 74 simple bone cyst patients were included (median age 9 years (range = 2-16), 56 (76%) male). Median follow-up was 2.9 years (range = 0.5-21). Index procedure was watchful waiting (n = 6), percutaneous procedure (n = 12), open procedure (n = 50), or osteosynthesis alone (n = 6). Median time until full weight-bearing was 8 weeks (95% confidence interval = 0.1-15.9) for watchful waiting, 9.5 (95% confidence interval = 3.7-15.3) for percutaneous procedure, 11 (95% confidence interval = -0.7 to 13.7) for open procedure, and 6.5 (95% confidence interval = 5.9-16.1) for osteosynthesis alone (p = 0.58). Failure rates were 33%, 58%, 29%, and 0%, respectively (p = 0.069). Overall failure-free survival at 1, 2, and 5 years was 77.8% (95% confidence interval = 68.2-87.4), 69.5% (95% confidence interval = 58.5-80.5), and 62.0% (95% confidence interval = 47.9-76.1), respectively. Conclusion: A preferred treatment for proximal femoral simple bone cysts remains unclear, with comparable failure rates and times until full weight-bearing. Watchful waiting may be successful in certain cases. If not feasible, osteosynthesis alone can be considered. Treatment goals should be cyst control, minimizing complications and swift return to normal activities. Therefore, an individualized balance should be made between undertreatment, with potentially higher complication risks versus overtreatment, resulting in possible larger interventions and accompanying complications. Level of evidence: Level IV, retrospective multicentre study.
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