Evidence map›Paper›PMID 38348290›Full record

ArticleSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society2024

Potentially active aspirin derivative to release nitric oxide:

Amruta M Amritkar, Afzal Hussain, Mohammad A Altamimi, Sumel Ashique, Mohd Usman Mohd Siddique, Sushil Burle, Anwar R Shaikh, Sameer N Goyal, Zahid R Bhat

Open access · hybridAbstract read
In one paragraph

Article in Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Amruta M AmritkarDepartment of Pharmaceutical Chemistry, Shri Vile Parle Kelavani Mandal's Institute of Pharmacy Dhule, MH 424001, India.
Afzal HussainDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Mohammad A AltamimiDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Sumel AshiqueDepartment of Pharmaceutical Sciences, Bengal College of Pharmaceutical Sciences & Research, Durgapur 713212, West Bengal, India.
Mohd Usman Mohd SiddiqueDepartment of Pharmaceutical Chemistry, Shri Vile Parle Kelavani Mandal's Institute of Pharmacy Dhule, MH 424001, India.
Sushil BurleSMT Kishoritai Bhoyar College of Pharmacy, New Kamptee, Nagpur, MH, India.
Anwar R ShaikhMCE's Society, Allana College of Pharmacy, Pune, MH, India.
Sameer N GoyalDepartment of Pharmacology, Shri Vile Parle Kelavani Mandal's Institute of Pharmacy Dhule, MH 424001, India.
Zahid R BhatDepartment of Molecular and Cellular oncology, MD Anderson Cancer Centre, Houston, TX, USA.
Shri Vile Parle Kelavani Mandal · INKing Saud University · SAHCG NCHRI Cancer Centre · INThe University of Texas MD Anderson Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The series of newer salicylate derivatives incorporating nitroxy functionality were synthesized and evaluated for their potential effect in gastrointestinal (GI) related toxicity produced by aspirin. The synthesized compounds (5a-j) were subjected to %NO (nitric oxide) release study,

Indexed as

Anti-inflammatory assessmentLD50 valueMD simulationPaw edema testSalicylate derivatives

Identifiers

PMID38348290
PMCPMC10859280
OpenAlexW4389903613

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.