Evidence map›Paper›PMID 38348241›Full record

ArticleERJ open research2024

Home noninvasive ventilation in severe COPD: in whom does it work and how?

Tim Raveling, Judith M Vonk, Nicholas S Hill, Peter C Gay, Ciro Casanova, Enrico Clini, Thomas Köhnlein, Eduardo Márquez-Martin, Tessa Schneeberger, Patrick B Murphy and 4 more

Open access · goldAbstract read
In one paragraph

Article in ERJ open research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Home Noninvasive Ventilation Should Start at Home.American journal of respiratory and critical care medicine · 2025
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 6 countries.

Tim RavelingDepartment of Pulmonary Diseases and Home Mechanical Ventilation, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.ORCID https://orcid.org/0000-0002-9125-9418
Judith M VonkGroningen Research Institute of Asthma and COPD, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.ORCID https://orcid.org/0000-0001-7531-4547
Nicholas S HillDivision of Pulmonary, Critical Care and Sleep Medicine, Tufts University Medical Center Boston, Boston, MA, USA.
Peter C GayDepartment of Pulmonary and Critical Care Medicine and the Center for Sleep Medicine, Mayo Clinic, Rochester, MN, USA.
Ciro CasanovaDepartment of Pulmonary, Research Unit, Hospital Universitario La Candelaria, Universidad de La Laguna, Tenerife, Spain.
Enrico CliniRespiratory Diseases Unit, Dept of Medical and Surgical Sciences SMECHIMAI, University Hospital of Modena Policlinico, University of Modena Reggio-Emilia, Modena, Italy.ORCID https://orcid.org/0000-0002-1515-5094
Thomas KöhnleinPneumological Specialist Center, Teuchern, Germany.
Eduardo Márquez-MartinMedical-Surgical Unit of Respiratory diseases, University Hospital Virgen del Rocío, Seville, Spain.
Tessa SchneebergerDepartment of Pulmonary Rehabilitation, Philipps-University of Marburg, Marburg, Germany.
Patrick B MurphyLane Fox Clinical Respiratory Physiology Research Unit, Guy's and St Thomas' NHS Foundation Trust, London, UK.ORCID https://orcid.org/0000-0002-1500-611X
Fransien M StruikDepartment of Pulmonary Diseases and Home Mechanical Ventilation, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Huib A M KerstjensDepartment of Pulmonary Diseases and Home Mechanical Ventilation, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.ORCID https://orcid.org/0000-0001-7705-7927
Marieke L DuivermanDepartment of Pulmonary Diseases and Home Mechanical Ventilation, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.ORCID https://orcid.org/0000-0002-8818-9447
Peter J WijkstraDepartment of Pulmonary Diseases and Home Mechanical Ventilation, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
University Medical Center Groningen · NLGuy's and St Thomas' NHS Foundation Trust · GBInstituto de Salud Carlos III · ESMayo Clinic · USPhilipps University of Marburg · DETufts University · USUniversidad de La Laguna · ESUniversity of Modena and Reggio Emilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Not all hypercapnic COPD patients benefit from home noninvasive ventilation (NIV), and mechanisms through which NIV improves clinical outcomes remain uncertain. We aimed to identify "responders" to home NIV, denoted by a beneficial effect of NIV on arterial partial pressure of carbon dioxide ( Methods: We used individual patient data from previous published trials collated for a systematic review. Linear mixed-effect models were conducted to compare the effect of NIV on Findings: Data of 1142 participants from 16 studies were used. Participants treated with lower pressure support (<14 Interpretation: With greater pressure support and better daily NIV usage, a larger improvement in

Identifiers

PMID38348241
PMCPMC10860207
OpenAlexW4391656227

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.