Evidence map›Paper›PMID 38348140›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2024

Transepithelial Accelerated Crosslinking for Progressive Keratoconus: A Critical Analysis of Medium-Term Treatment Outcomes.

Rodrigo Vilares-Morgado, Ana Margarida Ferreira, Ana Maria Cunha, Raúl Moreira, Luís Torrão, Pedro Neves-Cardoso, João Pinheiro-Costa

Abstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Transepithelial corneal cross-linking: a review.International ophthalmology · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rodrigo Vilares-MorgadoDepartment of Ophthalmology, Centro Hospitalar Universitário de São João, Porto, Portugal.ORCID 0000-0003-3325-2194
Ana Margarida FerreiraDepartment of Ophthalmology, Centro Hospitalar Universitário de São João, Porto, Portugal.ORCID 0009-0000-3592-2820
Ana Maria CunhaDepartment of Ophthalmology, Centro Hospitalar Universitário de São João, Porto, Portugal.ORCID 0000-0002-8519-8786
Raúl MoreiraDepartment of Ophthalmology, Centro Hospitalar Universitário de São João, Porto, Portugal.
Luís TorrãoDepartment of Ophthalmology, Centro Hospitalar Universitário de São João, Porto, Portugal.ORCID 0000-0003-0555-6860
Pedro Neves-CardosoDepartment of Ophthalmology, Centro Hospitalar Universitário de São João, Porto, Portugal.ORCID 0000-0002-2161-4680
João Pinheiro-CostaDepartment of Ophthalmology, Centro Hospitalar Universitário de São João, Porto, Portugal.ORCID 0000-0002-7289-4045

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To report the 4-year outcomes of transepithelial accelerated corneal collagen crosslinking (TE-ACXL) in the treatment of eyes with progressive keratoconus (KC). Methods: Eyes of patients who underwent TE-ACXL (6mW/cm Results: 41 eyes from 30 patients were included, with a mean age at crosslinking of 20.90±4.69 years. There was a significant increase in Kmean (+0.64±1.04 D, Conclusion: TE-ACXL proved to be a safe therapeutic option for progressive KC. However, its efficacy is deemed unsatisfactory, as a notable proportion of affected eyes may continue to advance within a 4-year timeframe, necessitating additional procedures to halt the disease's course.

Indexed as

epi-on crosslinkingkeratoconus progressionprogressive keratoconustrans-epithelial corneal crosslinking

Identifiers

PMID38348140
PMCPMC10860395

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.