Evidence map›Paper›PMID 38348037›Full record

ArticleFrontiers in immunology2024

Disentangling specific and unspecific components of innate immune memory in a copepod-tapeworm system.

Tze Hann Ng, Mark C Harrison, Jörn P Scharsack, Joachim Kurtz

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Recent Advances of Trained immunity in Macrophages.International journal of biological sciences · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tze Hann NgInstitute for Evolution and Biodiversity, University of Münster, Münster, Germany.
Mark C HarrisonInstitute for Evolution and Biodiversity, University of Münster, Münster, Germany.
Jörn P ScharsackInstitute for Evolution and Biodiversity, University of Münster, Münster, Germany.
Joachim KurtzInstitute for Evolution and Biodiversity, University of Münster, Münster, Germany.
University of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence that the innate immune system can respond with forms of memory upon reinfection has been accumulating over the past few years. These phenomena of "immune priming" in invertebrates, and "trained immunity" in vertebrates, are contrary to previous belief that immune memory and specificity are restricted to the adaptive immune system. However, while trained immunity is usually a response with rather low specificity, immune priming has shown highly specific responses in certain species. To date, it is largely unknown how specificity in innate immune memory can be achieved in response to different parasite types. Here, we revisited a system where an exceptionally high degree of innate immune specificity had been demonstrated for the first time, consisting of the copepod

Indexed as

CestodaCestode InfectionsCopepodaParasitesAnimalsHost-Parasite InteractionsImmunologic MemoryTrained Immunityimmune priminginnate immune specificityMacrocyclops albidusSchistocephalus solidustapeworm-copepod system

Identifiers

PMID38348037
PMCPMC10859752
OpenAlexW4391318129

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.