Evidence map›Paper›PMID 38347907›Full record

ArticleBioMed research international2024

Cystic Fibrosis Mice Are Highly Susceptible to Repeated Acute

Mariel Manzor, Sophia Koutsogiannaki, Marco DiBlasi, Matthew Schaefers, Gregory Priebe, Koichi Yuki

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mariel ManzorDepartment of Anesthesiology, Critical Care and Pain Medicine, Cardiac Anesthesia Division, Boston Children's Hospital, Boston, USA.
Sophia KoutsogiannakiDepartment of Anesthesiology, Critical Care and Pain Medicine, Cardiac Anesthesia Division, Boston Children's Hospital, Boston, USA.
Marco DiBlasiDepartment of Anesthesiology, Critical Care and Pain Medicine, Critical Care Division, Boston Children's Hospital, Boston, USA.
Matthew SchaefersDepartment of Anaesthesia, Harvard Medical School, Boston, USA.
Gregory PriebeDepartment of Anaesthesia, Harvard Medical School, Boston, USA.
Koichi YukiDepartment of Anesthesiology, Critical Care and Pain Medicine, Cardiac Anesthesia Division, Boston Children's Hospital, Boston, USA.ORCID https://orcid.org/0000-0003-1312-585X
Broad Institute · USBoston University · USBoston Children's Hospital · US

Funding

Optimization of anesthetic/sedative regimen for pulmonary pathophysiology in cystic fibrosis patientsR21AI158886 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI YUKI, KOICHI · 2021 to 2022
$487k
NIAID NIH HHS R21 AI158886
6 · The paper itself

Abstract

Cystic fibrosis (CF) is a genetic disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) that controls chloride current. A number of different CFTR transgenic mouse lines have been developed and subjected to both acute and chronic infection models. However, prior studies showed no substantial differences in bacterial clearance between CF and non-CF mice after single inoculations. Here, using F508del transgenic CF mice, we examined the role of repeated acute

Indexed as

Cystic FibrosisPneumoniaPseudomonas InfectionsAnimalsCystic Fibrosis Transmembrane Conductance RegulatorHumansMiceMice, TransgenicPersistent InfectionPseudomonas aeruginosaCystic Fibrosis Transmembrane Conductance Regulator

Identifiers

PMID38347907
PMCPMC10861279
OpenAlexW4391543313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.