Evidence map›Paper›PMID 38347745›Full record

ArticleInternational journal of aging & human development2025

Sleep Duration Polygenic Risk and Phenotype: Associations with Biomarkers of Accelerated Aging in the Baltimore Longitudinal Study of Aging.

David W Sosnowski, Emily J Smail, Brion S Maher, Ann Zenobia Moore, Pei-Lun Kuo, Mark N Wu, Dominique V Low, Katie L Stone, Eleanor M Simonsick, Luigi Ferrucci and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of aging & human development, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

David W SosnowskiDepartment of Mental Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0003-0007-7027
Emily J SmailDepartment of Mental Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Brion S MaherDepartment of Mental Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Ann Zenobia MooreLongitudinal Studies Section, Translational Gerontology Branch, Intramural Research Program, National Institute on Aging, Baltimore, MD, USA.
Pei-Lun KuoLongitudinal Studies Section, Translational Gerontology Branch, Intramural Research Program, National Institute on Aging, Baltimore, MD, USA.
Mark N WuDepartment of Neurology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Dominique V LowDepartment of Neurology, Yale University School of Medicine, New Haven, CT, USA.
Katie L StoneCalifornia Pacific Medical Center Research Institute, San Francisco, CA, USA.
Eleanor M SimonsickLongitudinal Studies Section, Translational Gerontology Branch, Intramural Research Program, National Institute on Aging, Baltimore, MD, USA.
Luigi FerrucciLongitudinal Studies Section, Translational Gerontology Branch, Intramural Research Program, National Institute on Aging, Baltimore, MD, USA.
Adam P SpiraDepartment of Mental Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.

Funding

The Baltimore Longitudinal Study Of AgingZIAAG000015 · NIA · NATIONAL INSTITUTE ON AGING · PI SIMONSICK, ELEANOR MARIE · 2009 to 2025
$116.9M
University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI Peihua Qiu · 2007 to 2026
$22.8M
EPIDEMIOLOGY AND BIOSTATISTICS OF AGINGT32AG000247 · NIA · JOHNS HOPKINS UNIVERSITY · PI Karen J. Bandeen-Roche · 1996 to 2026
$13.2M
Pharmacogenomics of ART adherence and effectiveness in the ALIVE CohortR01DA047064 · NIDA · JOHNS HOPKINS UNIVERSITY · PI KIRK, GREGORY D, MAHER, BRION S · 2018 to 2023
$5.8M
Multi-Institutional Training in Genetic/Genomic Approaches to Sleep DisordersT32HL110952 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CHERVIN, RONALD D, MIGNOT, EMMANUEL J · 2013 to 2022
$5.0M
Poor Sleep Altered Circadian Rhythms and Alzheimers DiseaseR01AG050507 · NIA · JOHNS HOPKINS UNIVERSITY · PI SPIRA, ADAM PETER · 2015 to 2019
$2.5M
Translational Research Training on Aging and Mobility (TRAM)T32AG062728 · NIA · UNIVERSITY OF FLORIDA · PI Todd Manini · 2020 to 2026
$2.0M
NHLBI NIH HHS T32 HL110952NIA NIH HHS P30 AG028740NIA NIH HHS R01 AG050507NIA NIH HHS T32 AG000247NIA NIH HHS T32 AG062728NIDA NIH HHS R01 DA047064
6 · The paper itself

Abstract

We sought to explore whether genetic risk for, and self-reported, short sleep are associated with biological aging and whether age and sex moderate these associations. Participants were a subset of individuals from the Baltimore Longitudinal Study of Aging who had complete data on self-reported sleep (

Indexed as

AgingMultifactorial InheritanceSleepAgedAged, 80 and overBaltimoreBiomarkersFemaleHumansLongitudinal StudiesMaleMiddle AgedPhenotypeRisk FactorsSleep DurationBiomarkersage accelerationagingbiomarkersepigeneticspolygenic risksleep duration

Identifiers

PMID38347745
PMCPMC11317550

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.