Evidence map›Paper›PMID 38347721›Full record

SynthesisEpidemiology and infection2024

Malaria in pregnancy: Meta-analyses of prevalence and associated complications.

Jai K Das, Sohail Lakhani, Abdu R Rahman, Faareha Siddiqui, Zahra Ali Padhani, Zainab Rashid, Omar Mahmud, Syeda Kanza Naqvi, Hamna Amir Naseem, Hamzah Jehanzeb and 2 more

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Epidemiology and infection, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  19. Current update on malaria in pregnancy: a systematic review.Tropical diseases, travel medicine and vaccines · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jai K DasInstitute for Global Health and Development, Aga Khan University, Karachi, Pakistan.
Sohail LakhaniDepartment of Community Health Sciences, Aga Khan University, Karachi, Pakistan.ORCID 0000-0003-3804-1978
Abdu R RahmanInstitute for Global Health and Development, Aga Khan University, Karachi, Pakistan.
Faareha SiddiquiInstitute for Global Health and Development, Aga Khan University, Karachi, Pakistan.
Zahra Ali PadhaniRobinson Research Institute, Adelaide Medical School, University of Adelaide, Adelaide, Australia.
Zainab RashidInstitute for Global Health and Development, Aga Khan University, Karachi, Pakistan.
Omar MahmudMedical College, Aga Khan University, Karachi, Pakistan.
Syeda Kanza NaqviInstitute for Global Health and Development, Aga Khan University, Karachi, Pakistan.
Hamna Amir NaseemInstitute for Global Health and Development, Aga Khan University, Karachi, Pakistan.
Hamzah JehanzebMedical College, Aga Khan University, Karachi, Pakistan.
Suresh KumarDepartment of Pathology, Jinnah Sindh Medical University, Karachi, Pakistan.
Mohammad Asim BegDepartment of Pathology and Laboratory Medicine, Aga Khan University, Karachi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review aims to assess the prevalence of malaria in pregnancy during antenatal visits and delivery, species-specific burden together with regional variation in the burden of disease. It also aims to estimate the proportions of adverse pregnancy outcomes in malaria-positive women. Based on the PRISMA guidelines, a thorough and systematic search was conducted in July 2023 across two electronic databases (including PubMed and CENTRAL). Forest plots were constructed for each outcome of interest highlighting the effect measure, confidence interval, sample size, and its associated weightage. All the statistical meta-analysis were conducted using R-Studio version 2022.07. Sensitivity analyses, publication bias assessment, and meta-regression analyses were also performed to ensure robustness of the review. According to the pooled estimates of 253 studies, the overall prevalence of malaria was 18.95% (95% CI: 16.95-21.11), during antenatal visits was 20.09% (95% CI: 17.43-23.06), and at delivery was 17.32% (95% CI: 14.47-20.61). The highest proportion of malarial infection was observed in Africa approximating 21.50% (95% CI: 18.52-24.81) during ANC and 20.41% (95% CI: 17.04-24.24) at the time of delivery. Our analysis also revealed that the odds of having anaemia were 2.40 times (95% CI: 1.87-3.06), having low birthweight were 1.99 times (95% CI: 1.60-2.48), having preterm birth were 1.65 times (95% CI: 1.29-2.10), and having stillbirths were 1.40 times (95% CI: 1.15-1.71) in pregnant women with malaria.

Indexed as

MalariaPregnancy Complications, ParasiticFemaleHumansPregnancyPregnancy OutcomePrevalenceepidemiologymalariameta-analysisprevalence

Identifiers

PMID38347721
PMCPMC10945947

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.