Evidence map›Paper›PMID 38347613›Full record

ArticleBMC chemistry2024

Novel quinazolines bearing 1,3,4-thiadiazole-aryl urea derivative as anticancer agents: design, synthesis, molecular docking, DFT and bioactivity evaluations.

Sara Masoudinia, Marjaneh Samadizadeh, Maliheh Safavi, Hamid Reza Bijanzadeh, Alireza Foroumadi

Abstract read
In one paragraph

Article in BMC chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sara MasoudiniaDepartment of Chemistry, Islamic Azad University, Central Tehran Branch, Tehran, Iran.
Marjaneh SamadizadehDepartment of Chemistry, Islamic Azad University, Central Tehran Branch, Tehran, Iran. drm.samadizadeh@gmail.com.
Maliheh SafaviDepartment of Biotechnology, Iranian Research Organization for Science and Technology (IROST), Tehran, Iran.
Hamid Reza BijanzadehDepartment of Environment, Faculty of Natural Resources and Marine Sciences, Tarbiat Modares University, Tehran, Iran.
Alireza ForoumadiDepartment of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran. aforoumadi@yahoo.com.

Funding

Faculty of Pharmacy, Tehran University of Medical Sciences 1402-1-104-65425
6 · The paper itself

Abstract

A novel series of 1-(5-((6-nitroquinazoline-4-yl)thio)-1,3,4-thiadiazol-2-yl)-3-phenylurea derivatives 8 were designed and synthesized to evaluate their cytotoxic potencies. The structures of these obtained compounds were thoroughly characterized by IR,

Indexed as

AnticancerIn silico ADMEMolecular dockingMTT assayQuinazoline

Identifiers

PMID38347613
PMCPMC10863284

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.