Evidence map›Paper›PMID 38347580›Full record

ArticleJournal of medical case reports2024

Corticosteroid treatment for acute hydrocephalus in neurosarcoidosis: a case report.

Edoardo Dalmato Schilke, Giulia Remoli, Claudia Cutellé, Claudia Balducci, Diletta Cereda, Maria Letizia Fusco, Lucio Tremolizzo, Carlo Ferrarese, Ildebrando Appollonio, Maura Frigo

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Edoardo Dalmato SchilkeNeurology Department, Fondazione IRCCS San Gerardi Dei Tintori, San Gerardo Hospital, Monza. Via G.Pergolesi, 33, 20900, Monza, Italy. schilkeedoardo@gmail.com.
Giulia RemoliNeurology Department, Fondazione IRCCS San Gerardi Dei Tintori, San Gerardo Hospital, Monza. Via G.Pergolesi, 33, 20900, Monza, Italy.
Claudia CutelléNeurology Department, Fondazione IRCCS San Gerardi Dei Tintori, San Gerardo Hospital, Monza. Via G.Pergolesi, 33, 20900, Monza, Italy.
Claudia BalducciNeurology Department, Fondazione IRCCS San Gerardi Dei Tintori, San Gerardo Hospital, Monza. Via G.Pergolesi, 33, 20900, Monza, Italy.
Diletta CeredaNeurology Department, Fondazione IRCCS San Gerardi Dei Tintori, San Gerardo Hospital, Monza. Via G.Pergolesi, 33, 20900, Monza, Italy.
Maria Letizia FuscoNeurology Department, Fondazione IRCCS San Gerardi Dei Tintori, San Gerardo Hospital, Monza. Via G.Pergolesi, 33, 20900, Monza, Italy.
Lucio TremolizzoNeurology Department, Fondazione IRCCS San Gerardi Dei Tintori, San Gerardo Hospital, Monza. Via G.Pergolesi, 33, 20900, Monza, Italy.
Carlo FerrareseNeurology Department, Fondazione IRCCS San Gerardi Dei Tintori, San Gerardo Hospital, Monza. Via G.Pergolesi, 33, 20900, Monza, Italy.
Ildebrando AppollonioNeurology Department, Fondazione IRCCS San Gerardi Dei Tintori, San Gerardo Hospital, Monza. Via G.Pergolesi, 33, 20900, Monza, Italy.
Maura FrigoNeurology Department, Fondazione IRCCS San Gerardi Dei Tintori, San Gerardo Hospital, Monza. Via G.Pergolesi, 33, 20900, Monza, Italy.
Azienda Ospedaliera San Gerardo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeurosarcoidosis occurs symptomatically in 5-10% of patients with sarcoidosis, and hydrocephalus is a rare complication of neurosarcoidosis, with either acute or subacute onset and presenting symptoms related to increased intracranial pressure. It represents a potentially fatal manifestation with a mortality rate of 22% (increased to 75% in case of coexistence of seizures) that requires a prompt initiation of treatment. High-dose intravenous corticosteroid treatment and neurosurgical treatment must be considered in all cases of neurosarcoidosis hydrocephalus. CASE PRESENTATION: Here we present a case of hydrocephalus in neurosarcoidosis, complicated by generalized seizures, in a 29-year-old Caucasian male patient treated with medical treatment only, with optimal response.

conclusionSince neurosurgery treatment can lead to severe complications, this case report underlines the possibility to undergo only medical treatment in selected cases. Further studies are needed to stratify patients and better identify those eligible for only medical approach.

Indexed as

Central Nervous System DiseasesHydrocephalusSarcoidosisAdrenal Cortex HormonesAdultHumansMaleSeizuresAdrenal Cortex HormonesNeuroimmunologyNeurosarcoidosisNeurosurgery in sarcoidosisObstructive hydrocephalus

Identifiers

PMID38347580
PMCPMC10863230
OpenAlexW4392729567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.