ArticleBMC cardiovascular disorders2024
Coronary artery disease incidence, risk factors, awareness, and medication utilization in a 10-year cohort study.
Article in BMC cardiovascular disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Which antiplatelet is better after stents? A meta-analysis of aspirin vs clopidogrel in the maintenance phase.Naunyn-Schmiedeberg's archives of pharmacology · 2026Pooled it
- Enhancing self-care in post-MI patients: a family-supported educational intervention based on the theory of planned behavior.BMC cardiovascular disorders · 2025Trial
- Cardiovascular Diseases and All-Cause Mortality Risk in Patients With Prehypertension and Noncommunicable Diseases: Results From the Kailuan Study.Journal of clinical hypertension (Greenwich, Conn.) · 2026Article
- Comparative evaluation of nine insulin resistance indices for 10-year coronary artery disease risk prediction in non-diabetic adults.Scientific reports · 2026Article
- Higher Dietary Antioxidant Index Is Associated with Better Lipid Profile in Women with Coronary Artery Disease.Healthcare (Basel, Switzerland) · 2026Article
- Hypertension and 10-year risk of coronary artery diseases in adult population: Yazd healthy heart project.ARYA atherosclerosis · 2026Article
- The association of remnant cholesterol inflammatory index with the risk of major adverse cardiovascular events in patients with angina undergoing percutaneous coronary intervention: a retrospective study.Frontiers in cardiovascular medicine · 2026Article
- Coronary artery patient's empowerment through a user-centered design of an electronic personal health record: A qualitative study.Journal of education and health promotion · 2026Article
- Prevalence of Coronary Artery Diseases Among Adult Women Residents of Tehran: A Cross-Sectional Report From Tehran Cohort Study (TeCS).Cardiology research and practice · 2026Article
- Article
- Apolipoprotein E ε3/ε4 and coronary artery disease: lipid and non-lipid mechanisms in personalized prevention - narrative review.Frontiers in cardiovascular medicine · 2026Review
- Role of Glycolysis and Nitric Oxide Pathway Crosstalk in Macrophages in Atherosclerosis.Current medicinal chemistry · 2026Review
- Review
- Inflammatory dietary scores and their association with clinical outcomes in coronary heart disease.Frontiers in nutrition · 2026Article
- Essential and Toxic Elements in Cardiovascular Disease: Pathophysiological Roles and the Emerging Contribution of Hair Mineral Analysis.International journal of molecular sciences · 2025Review
- Exploring the experiences and rehabilitation needs of patients with coronary artery diseases: an effort to design a contextual home-based cardiac rehabilitation through a qualitative enquiry.BMC sports science, medicine & rehabilitation · 2025Article
- Article
- Serum uric acid and coronary artery disease risk: a 10-year prospective cohort study in healthy adults.BMC cardiovascular disorders · 2025Observational
- Article
- The additional impact of metabolic syndrome on left ventricular deformation and myocardial energetic efficiency impairment in ischemia with nonobstructive coronary arteries patients.Cardiovascular diabetology · 2025Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is a substantial disparity in coronary artery disease (CAD) burden between Iran and other nations that place a strong emphasis on the assessment of CAD risk factors and individuals' awareness and ability to control them.
methodsTwo thousand participants of a community-based Iranian population aged 20-74 years were investigated with a mean follow-up of 9.9 years (range: 7.6 to 12.2). An analysis of Cox regression was conducted to determine the association between CAD development and classic risk factors such as age, sex, smoking, physical activity, education, obesity, dyslipidemia, hypertension, and diabetes mellitus. Furthermore, we computed the population attributable fraction for these risk factors.
resultsAfter a follow-up period of nearly 10 years, 225 CAD events were reported, constituting 14.5% of the overall incidence. Nighty three percent of participants had more than one risk factor. Age was the most predictive risk factor, with a hazard ratio (HR) and confidence interval (CI) of 5.56 (3.87-7.97, p < 0.001) in men older than 45 and females older than 55 compared to lower ages. In comparison to females, males had an HR of 1.45 (CI: 1.11-1.90, p value = 0.006) for developing CAD. Nearly 80% of the patients had dyslipidemia, with a hazard ratio of 2.19 (CI: 1.40-3.44, p = 0.01). Among the participants, 28.9% had hypertension, and 52% had prehypertension, which had HRs of 4.1 (2.4-7.2, p < 0.001) and 2.4 (1.4-4.2, p < 0.001), respectively. Diabetes, with a prevalence of 17%, had an HR of 2.63 (CI: 2 -3.47, p < 0.001), but prediabetes was not significantly associated with CAD. Awareness of diabetes, dyslipidemia, and hypertension was 81%, 27.9%, and 48.1%, respectively. Regarding medication usage, the corresponding percentages were 51% for diabetes, 13.2% for dyslipidemia, and 41% for hypertension.
conclusionsCompared to previous studies in Iran and neighboring countries, the current study found a higher incidence of CAD, more prevalent risk factors, and a lower awareness and ability to control these risk factors. Thus, an effective preventive strategy is needed to reduce the CAD burden in Iran.
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