Evidence map›Paper›PMID 38347431›Full record

ArticleDrug delivery and translational research2024

Stimuli-responsive magnetic silica-poly-lactic-co-glycolic acid hybrid nanoparticles for targeted cancer chemo-immunotherapy.

Anuradha Gupta, Karishma Niveria, Hitesh Harsukhbhai Chandpa, Mamta Singh, Vikas Kumar, Amulya Kumar Panda, Jairam Meena

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Article in Drug delivery and translational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Anuradha GuptaSchool of Material Science and Technology, Indian Institute of Technology (BHU) Varanasi, Varanasi, 221005, India.
Karishma NiveriaNanobiotech Lab, Department of Zoology, Kirori Mal College, University of Delhi, Delhi, 110007, India.
Hitesh Harsukhbhai ChandpaImmunoEngineering and Therapeutics Laboratory, Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology (BHU) Varanasi, Varanasi, 221005, India.
Mamta SinghProduct Development Cell, National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi, 110067, India.
Vikas KumarCell Biology Lab, Kusuma School of Biological Sciences, Indian Institute of Technology, New Delhi, 110067, India.
Amulya Kumar PandaProduct Development Cell, National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi, 110067, India.
Jairam MeenaProduct Development Cell, National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi, 110067, India. jairam.phe@itbhu.ac.in.ORCID 0000-0002-7625-6817
National Institute of Immunology · INIndian Institute of Technology BHU · INIndian Institute of Technology Delhi · INUniversity of Delhi · IN

Funding

Indian Council of Medical Research File no. 5/3/8/39/ITR-F/2019SERB DST File no. PDF/2022/003287
6 · The paper itself

Abstract

Chemotherapy and immunotherapy are two important modalities in cancer management. However, due to multiple reasons, a monotherapy is only partially effective. Hence, if used concurrently in targeted and stimuli-responsive manner, it could have been superior therapeutically. To facilitate co-delivery of chemotherapeutic and immunotherapeutic agent to the target cancer cells, engineered nanoparticles, i.e., a pH-responsive polymer PLGA-coated magnetic silica nanoparticles (Fe

Indexed as

B7-H1 AntigenImmunotherapyMice, Inbred BALB CPaclitaxelPolylactic Acid-Polyglycolic Acid CopolymerRNA, Small InterferingSilicon DioxideAnimalsAntineoplastic Agents, PhytogenicApoptosisCell Line, TumorDrug CarriersDrug LiberationFemaleHumansHydrogen-Ion ConcentrationAntineoplastic Agents, PhytogenicB7-H1 AntigenDrug CarriersMagnetite NanoparticlesPaclitaxelPolylactic Acid-Polyglycolic Acid CopolymerRNA, Small InterferingSilicon DioxideImmunotherapyMagnetic- silica nanoparticlesPaclitaxelPolydopamine (PDA)Poly-lactic co-glycolic acid (PLGA)Programmed cell death ligand-1 (PD-L1)Small-interfering RNA (siRNA)

Identifiers

PMID38347431
OpenAlexW4391756120

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.