Evidence map›Paper›PMID 38347294›Full record

ArticleBiological trace element research2024

Plasma Levels of Magnesium, Calcium, Calcium to Magnesium Ratio, and Associations with Metabolic Syndrome and Cardiometabolic Risk Factors.

Melissa Nunes Moia, Severina Carla Vieira Cunha Lima, Francisca Leide da Silva Nunes, Salomão Israel Monteiro Lourenço Queiroz, Dirce Maria Lobo Marchioni, Lucia Fátima Campos Pedrosa, Fernando Barbosa, Clélia de Oliveira Lyra, Karine Cavalcanti Maurício Sena-Evangelista

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In one paragraph

Article in Biological trace element research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. The evaluation of serum magnesium and calcium/magnesium ratio in patients with breast cancer receiving adjuvant chemotherapy.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Melissa Nunes MoiaPostgraduate Program in Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho 3000 - Lagoa Nova, Natal, Rio Grande do Norte, 59078-900, Brazil.
Severina Carla Vieira Cunha LimaDepartment of Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho 3000 - Lagoa Nova, Natal, Rio Grande do Norte, 59078-900, Brazil.
Francisca Leide da Silva NunesPostgraduate Program in Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho 3000 - Lagoa Nova, Natal, Rio Grande do Norte, 59078-900, Brazil.
Salomão Israel Monteiro Lourenço QueirozPostgraduate Program in Collective Health, Health Sciences Center, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho 3000 - Lagoa Nova, Natal, Rio Grande do Norte, 59078-900, Brazil.
Dirce Maria Lobo MarchioniDepartment of Nutrition, School of Public Health, University of São Paulo, São Paulo Campus, Av. Dr. Arnaldo, 715 - Cerqueira César, São Paulo, São Paulo, 01246-904, Brazil.
Lucia Fátima Campos PedrosaPostgraduate Program in Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho 3000 - Lagoa Nova, Natal, Rio Grande do Norte, 59078-900, Brazil.
Fernando BarbosaLaboratory of Clinical, Toxicological and Bromatological Analysis, Faculty of Pharmaceutical Sciences, University of São Paulo, Ribeirão Preto Campus, Av. Do Café, s/n - Monte Alegre, Ribeirão Preto, São Paulo, 14040-903, Brazil.
Clélia de Oliveira LyraDepartment of Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho 3000 - Lagoa Nova, Natal, Rio Grande do Norte, 59078-900, Brazil.
Karine Cavalcanti Maurício Sena-EvangelistaDepartment of Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho 3000 - Lagoa Nova, Natal, Rio Grande do Norte, 59078-900, Brazil. karine.sena@ufrn.br.
Universidade Federal do Rio Grande do Norte · BRUniversidade de São Paulo · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 431053/2016-2Coordenação de Aperfeiçoamento de Pessoal do Nível Superior - CAPES 001Fundação de Amparo à Pesquisa do Estado de São Paulo 2018/ 24069-3
6 · The paper itself

Abstract

Magnesium and calcium are elements that have been associated with cardiometabolic risk factors related to metabolic syndrome (MetS). However, there are gaps in the knowledge regarding the impact of the calcium to magnesium (Ca/Mg) ratio in plasma. Thus, we aim to evaluate the associations between magnesium and calcium levels in plasma, and the Ca/Mg ratio in plasma with MetS components and other cardiometabolic risk factors. This cross-sectional study was carried out with 112 adults and older people, distributed into groups with (n = 60) and without MetS (n = 52). We evaluated sociodemographic, anthropometric, and biochemical data. Magnesium and calcium levels in plasma were measured by inductively coupled plasma mass spectrometry technique (ICP-MS). There was a high frequency of MetS, with no significant differences in magnesium and calcium levels and Ca/Mg ratio in plasma observed between groups. There were no associations between magnesium and MetS components or other cardiometabolic risk factors (all p > 0.05). Calcium levels were associated with total cholesterol (β =  - 0.020; p = 0.000) and high-density lipoprotein cholesterol (HDL-c) (β =  - 0.046; p = 0.005). The total cholesterol (β =  - 0.025; p = 0.000) and low-density lipoprotein cholesterol (LDL-c) (β = 0.017; p = 0.020) were preditors of the Ca/Mg ratio. These results indicate important associations of calcium and the Ca/Mg ratio in plasma with cardiometabolic risk factors related to MetS.

Indexed as

CalciumCardiometabolic Risk FactorsMagnesiumMetabolic SyndromeAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedRisk FactorsCalciumMagnesiumCalcium to magnesium ratioCardiometabolic riskCholesterolLipid profileMetabolic syndrome

Identifiers

PMID38347294
OpenAlexW4391740516

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.