Evidence map›Paper›PMID 38347282›Full record

ArticlePediatric nephrology (Berlin, Germany)2024

The effect of gastrostomy tube feeding on growth in children with chronic kidney disease and on dialysis.

Abdulelah Alshaiban, Adebola Osuntoki, Shelley Cleghorn, Antonia Loizou, Rukshana Shroff

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Malnutrition management in children with chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Abdulelah AlshaibanUCL Great Ormond Street Institute of Child Health, University College London, London, WC1N 3JH, UK.ORCID 0000-0001-7957-7213
Adebola OsuntokiUCL Great Ormond Street Institute of Child Health, University College London, London, WC1N 3JH, UK.
Shelley CleghornUCL Great Ormond Street Institute of Child Health, University College London, London, WC1N 3JH, UK.
Antonia LoizouUCL Great Ormond Street Institute of Child Health, University College London, London, WC1N 3JH, UK.
Rukshana ShroffUCL Great Ormond Street Institute of Child Health, University College London, London, WC1N 3JH, UK. Rukshana.Shroff@gosh.nhs.uk.
University College London · GBGreat Ormond Street Hospital · GBKing Saud Medical City · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastrostomy tube (GT) feeding is used to promote nutrition and growth in children with chronic kidney disease (CKD). We explored the relationship between gastrostomy feeding and growth parameters in children with CKD, looking specifically at the nutritional composition of feeds.

methodsChildren with CKD stages 3-5 or on dialysis in a tertiary children's kidney unit were studied. Data on anthropometry, biochemistry, and nutritional composition of feeds were collected from the time of GT insertion for 3 years or until transplantation.

resultsForty children (18 female) were included. Nineteen children were on peritoneal dialysis, 8 on hemodialysis, and 13 had CKD stages 3-5. The median (interquartile range [IQR]) age at GT insertion was 1.26 (0.61-3.58) years, with 31 (77.5%) under 5 years of age. The median duration of gastrostomy feeding was 5.32 (3.05-6.31) years. None received growth hormone treatment. Children showed a significant increase in weight standard deviation score (SDS) (p = 0.0005), weight-for-height SDS (p = 0.0007) and body mass index (BMI) SDS (p < 0.0001). None of the children developed obesity. Although not statistically significant, the median height-SDS increased into the normal range (from -2.29 to -1.85). Weight-SDS positively correlated with the percentage of energy requirements from feeds (p = 0.02), and the BMI-SDS correlated with the percentage of total energy intake as fat (p < 0.001).

conclusionGT feeding improves weight-SDS and BMI-SDS without leading to obesity. GT feeding improved height-SDS but this did not reach statistical significance, suggesting that factors in addition to nutritional optimization need to be considered for statural growth.

Indexed as

Enteral NutritionGastrostomyRenal DialysisRenal Insufficiency, ChronicBody HeightBody Mass IndexChildChild, PreschoolFemaleHumansInfantMaleNutritional StatusChildrenChronic kidney diseaseGastrostomy tube feedingGrowthNutritionObesity

Identifiers

PMID38347282
PMCPMC11349843
OpenAlexW4391783850

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.