ArticleNature neuroscience2024
A molecularly defined amygdala-independent tetra-synaptic forebrain-to-hindbrain pathway for odor-driven innate fear and anxiety.
Article in Nature neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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Who cites it
21 citing papers in PubMed, 27 citations in OpenAlex.
- Cannabinoid modulation of central amygdala population dynamics during threat investigation.Nature communications · 2026Article
- A Molecularly Defined Midbrain Circuit Mechanism for Sound-Driven Defensive Behavior and Anxiety.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Bidirectional influences and clinical implications of psychological factors and oral health during orthodontic treatment.The Saudi dental journal · 2026Review
- Standardized chronic restraint stress protocols reveal dynamic evolution of behavioral adaptations in male mice: implications for translational neuroscience.Molecular psychiatry · 2026Article
- Sustained hyperactivity of parasubthalamic nucleus by PACAP signaling mediates stress-induced anxiety.Molecular psychiatry · 2026Article
- Article
- Functional remodeling of the parasubthalamic nucleus drives alcohol drinking escalation in dependence.bioRxiv : the preprint server for biology · 2026Article
- An intralayer microcircuit in the temporal association cortex underlies sensory-induced escape in mice.Nature communications · 2026Article
- Delta Opioid Receptors within the Cortico-Thalamic Circuitry Underlie Hyperactivity Induced by High-Dose Morphine.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- A nose-to-brain axis for spoiled food odor-triggered defensive responses in male mice.Nature communications · 2026Article
- Discovery of a long-acting nanocrystal formulation of INND-2201, a new co-drug of pregabalin and palmitoylethanolamide with synergistic analgesic effects.Pharmaceutical science advances · 2025Article
- A noncanonical parasubthalamic nucleus-to-extended amygdala circuit converts chronic social stress into anxiety.The Journal of clinical investigation · 2025Article
- Precise rewiring of corticospinal axons and spinal interneurons via near-infrared optogenetics for spinal cord injury treatment.Science advances · 2025Article
- Anterior cingulate cortex parvalbumin and somatostatin interneurons shape social behavior in male mice.Nature communications · 2025Article
- Tachykinin-1-expressing parasubthalamic nucleus neurons are necessary for odorant-induced appetite suppression.Physiology & behavior · 2025Article
- Review
- Theoretical analysis of low-power deep synergistic sono-optogenetic excitation of neurons by co-expressing light-sensitive and mechano-sensitive ion-channels.Communications biology · 2025Article
- Tandospirone prevents anesthetic-induced respiratory depression through 5-HTScientific reports · 2025Article
- "Now You See Me": A Neural Pathway Independent of the Amygdala Responsible for Fear and Anxiety.Neuroscience bulletin · 2025Article
- Hunger guides immunity to friend versus foe.Nature neuroscience · 2024Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
Abstract
Fear-related disorders (for example, phobias and anxiety) cause a substantial public health problem. To date, studies of the neural basis of fear have mostly focused on the amygdala. Here we identify a molecularly defined amygdala-independent tetra-synaptic pathway for olfaction-evoked innate fear and anxiety in male mice. This pathway starts with inputs from the olfactory bulb mitral and tufted cells to pyramidal neurons in the dorsal peduncular cortex that in turn connect to cholecystokinin-expressing (Cck
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.