Evidence map›Paper›PMID 38346884›Full record

ArticleBMJ open2024

Assessing trends and variability in outpatient dual testing for chronic kidney disease with urine albumin and serum creatinine, 2009-2018: a retrospective cohort study in the Veterans Health Administration System.

Nicole M Bhave, Yun Han, Diane Steffick, Jennifer Bragg-Gresham, Kara Zivin, Nilka R Burrows, Meda E Pavkov, Delphine Tuot, Neil R Powe, Rajiv Saran

Abstract read
In one paragraph

Article in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Nicole M Bhave *Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Yun Han *Department of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, Michigan, USA hanyun@umich.edu rsaran@umich.edu.ORCID 0000-0002-3847-3757
Diane SteffickDepartment of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, Michigan, USA.
Jennifer Bragg-GreshamDepartment of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0002-9069-9489
Kara ZivinCenter for Clinical Management Research, VA Ann Arbor Health Care System, Ann Arbor, Michigan, USA.
Nilka R BurrowsDivision of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Meda E PavkovDivision of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Delphine TuotDepartment of Medicine, Division of Nephrology, University of California San Francisco, San Francsisco, California, USA.
Neil R PoweDepartment of Medicine, Division of Nephrology, University of California San Francisco, San Francsisco, California, USA.
Rajiv SaranDepartment of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, Michigan, USA hanyun@umich.edu rsaran@umich.edu.

Funding

HSR&D Research Career Scientist AwardIK6HX003397 · VA · VETERANS HEALTH ADMINISTRATION · PI Kara Zivin · 2021 to 2026
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HSRD VA IK6 HX003397NCCDPHP CDC HHS U58 DP006254
6 · The paper itself

Abstract

backgroundSimultaneous urine testing for albumin (UAlb) and serum creatinine (SCr), that is, 'dual testing,' is an accepted quality measure in the management of diabetes. As chronic kidney disease (CKD) is defined by both UAlb and SCr testing, this approach could be more widely adopted in kidney care.

objectiveWe assessed time trends and facility-level variation in the performance of outpatient dual testing in the integrated Veterans Health Administration (VHA) system. DESIGN, SUBJECTS AND MAIN MEASURES: This retrospective cohort study included patients with any inpatient or outpatient visit to the VHA system during the period 2009-2018. Dual testing was defined as UAlb and SCr testing in the outpatient setting within a calendar year. We assessed time trends in dual testing by demographics, comorbidities, high-risk (eg, diabetes) specialty care and facilities. A generalised linear mixed-effects model was applied to explore individual and facility-level predictors of receiving dual testing. KEY

resultsWe analysed data from approximately 6.9 million veterans per year. Dual testing increased, on average, from 17.4% to 21.2%, but varied substantially among VHA centres (0.3%-43.7% in 2018). Dual testing was strongly associated with diabetes (OR 10.4, 95% CI 10.3 to 10.5, p<0.0001) and not associated with VHA centre complexity level. However, among patients with high-risk conditions including diabetes, <50% received dual testing in any given year. As compared with white veterans, black veterans were less likely to be tested after adjusting for other individual and facility characteristics (OR 0.93, 95% CI 0.92 to 0.93, p<0.0001).

conclusionsDual testing for CKD in high-risk specialties is increasing but remains low. This appears primarily due to low rates of testing for albuminuria. Promoting dual testing in high-risk patients will help to improve disease management and patient outcomes.

Indexed as

Diabetes MellitusRenal Insufficiency, ChronicVeteransCreatinineHumansOutpatientsRetrospective StudiesUnited StatesUnited States Department of Veterans AffairsVeterans HealthCreatinineGENERAL MEDICINE (see Internal Medicine)NephrologyPrimary Health Care

Identifiers

PMID38346884
PMCPMC10862291

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.