ArticleEnvironmental health and preventive medicine2024
Non-linear association between long-term air pollution exposure and risk of metabolic dysfunction-associated steatotic liver disease.
Article in Environmental health and preventive medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between air pollution and risk of non-alcoholic fatty liver disease: an updated meta-analysis.Frontiers in public health · 2025Pooled it
- Combined effects of nitrogen dioxide and ozone air pollution on maternal liver function during pregnancy: a birth cohort study in China.Environmental health and preventive medicine · 2026Article
- DeepDiff-SHAP: Interpretable deep learning for subgroup-specific causal hypothesis generation using conditional SHAP.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing · 2026Article
- Environmental determinants of male infertility: emerging threats and technological interventions.Frontiers in medicine · 2026Review
- The impact of extreme air pollution on preterm birth in twin pregnancies: identifying susceptible exposure windows.Annals of medicine · 2025Article
- Fine particulate matter exposure and risk of scooter collisions among older adults.Injury epidemiology · 2025Article
- The Impact of Air Pollution on the Lung-Gut-Liver Axis: Oxidative Stress and Its Role in Liver Disease.Antioxidants (Basel, Switzerland) · 2025Review
- The Role of Extracellular Vesicles in the Pathogenesis of Metabolic Dysfunction-Associated Steatotic Liver Disease and Other Liver Diseases.International journal of molecular sciences · 2025Review
- Life-threatening risk factors contribute to the development of diseases with the highest mortality through the induction of regulated necrotic cell death.Cell death & disease · 2025Review
- A population-based study on meteorological conditions in association with motor vehicle collisions among people with type 2 diabetes.Environmental health and preventive medicine · 2025Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMetabolic Dysfunction-associated Steatotic Liver Disease (MASLD) has become a global epidemic, and air pollution has been identified as a potential risk factor. This study aims to investigate the non-linear relationship between ambient air pollution and MASLD prevalence.
methodIn this cross-sectional study, participants undergoing health checkups were assessed for three-year average air pollution exposure. MASLD diagnosis required hepatic steatosis with at least 1 out of 5 cardiometabolic criteria. A stepwise approach combining data visualization and regression modeling was used to determine the most appropriate link function between each of the six air pollutants and MASLD. A covariate-adjusted six-pollutant model was constructed accordingly.
resultsA total of 131,592 participants were included, with 40.6% met the criteria of MASLD. "Threshold link function," "interaction link function," and "restricted cubic spline (RCS) link functions" best-fitted associations between MASLD and PM
conclusionNon-linear associations were found between air pollutants and MASLD prevalence. PM
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