ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2024
Where you live matters: Area deprivation predicts poor survival and liver transplant waitlisting.
Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Social Disadvantage and Disparities in Chronic Liver Disease: A Systematic Review.The American journal of gastroenterology · 2024Pooled it
- Residential and Transplant Center Neighborhood Segregation and Live Donor Liver Transplant.JAMA network open · 2026Article
- Longitudinal Changes in the Impact of Socioeconomic Status on Graft Failure in Kidney Transplantation.Kidney360 · 2026Article
- State-Level Geographic Disparities in Liver Transplant Access: Waitlist Outcome Patterns.Journal of clinical medicine · 2026Article
- Role of social determinants and outcomes of patients with alcohol-associated liver disease referred for early liver transplantation: A multicenter analysis.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2026Article
- Spontaneous Recovery and Mortality in Patients With ALD Referred for Early Liver Transplantation.The American journal of gastroenterology · 2026Article
- Neighborhood Social Cohesion Associated With Chronic Liver Disease Prevalence and All-Cause Mortality.Gastro hep advances · 2026Article
- Evaluating the impact of neighborhood socioenvironmental burden on patient characteristics and survival in liver transplant recipients.Frontiers in transplantation · 2026Article
- Measuring health inequalities in liver transplantation: a systematic review of deprivation scores for survival in end-stage liver disease.BMJ public health · 2026Article
- Exploring Caregiver Support as a Potential Mediator of Neighborhood Socioeconomic Disadvantage and Reduced Likelihood of Liver Transplant Waitlisting.Transplantation direct · 2025Article
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Authors and funding
12 authors at 1 institution in 2 countries.
Funding
Abstract
Social determinants of health (SDOH) are important predictors of poor clinical outcomes in chronic diseases, but their associations among the general cirrhosis population and liver transplantation (LT) are limited. We conducted a retrospective, multiinstitutional analysis of adult (≥18-years-old) patients with cirrhosis in metropolitan Chicago to determine the associations of poor neighborhood-level SDOH on decompensation complications, mortality, and LT waitlisting. Area deprivation index and covariates extracted from the American Census Survey were aspects of SDOH that were investigated. Among 15 101 patients with cirrhosis, the mean age was 57.2 years; 6414 (42.5%) were women, 6589 (43.6%) were non-Hispanic White, 3652 (24.2%) were non-Hispanic Black, and 2662 (17.6%) were Hispanic. Each quintile increase in area deprivation was associated with poor outcomes in decompensation (sHR [subdistribution hazard ratio] 1.07; 95% CI 1.05-1.10; P < .001), waitlisting (sHR 0.72; 95% CI 0.67-0.76; P < .001), and all-cause mortality (sHR 1.09; 95% CI 1.06-1.12; P < .001). Domains of SDOH associated with a lower likelihood of waitlisting and survival included low income, low education, poor household conditions, and social support (P < .001). Overall, patients with cirrhosis residing in poor neighborhood-level SDOH had higher decompensation, and mortality, and were less likely to be waitlisted for LT. Further exploration of structural barriers toward LT or optimizing health outcomes is warranted.
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