Evidence map›Paper›PMID 38346237›Full record

Trial reportAmerican journal of respiratory and critical care medicine2024

Alveolar Hemorrhage in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: Results of an International Randomized Controlled Trial (PEXIVAS).

Lynn A Fussner, Luis Felipe Flores-Suárez, Rodrigo Cartin-Ceba, Ulrich Specks, P Gerard Cox, David R W Jayne, Peter A Merkel, Michael Walsh, PEXIVAS Investigators

Open access · greenAbstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in American journal of respiratory and critical care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
13.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Guideline
  2. [Management of emergencies in rheumatology].Zeitschrift fur Rheumatologie · 2026
    Review
  3. Article
  4. Review
  5. Review
  6. [Management of emergencies in rheumatology].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Management of severe acute pulmonary haemorrhage in children.The Lancet. Child & adolescent health · 2025
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 4 countries.

Lynn A FussnerDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, The Ohio State University, Columbus, Ohio.ORCID 0000-0003-0944-0216
Luis Felipe Flores-SuárezLa Clínica de Vasculitis Sistémicas Primarias, Instituto Nacional de Enfermedades Respiratorias, Tlalpan, Ciudad de México, Mexico.ORCID 0000-0002-0172-8023
Rodrigo Cartin-CebaDivision of Pulmonary Medicine, Department of Internal Medicine, Mayo Clinic, Scottsdale, Arizona.ORCID 0000-0001-6738-9821
Ulrich SpecksDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota.ORCID 0000-0002-6559-1206
P Gerard CoxDivision of Respirology and.ORCID 0000-0002-3104-8600
David R W JayneDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0002-1712-0637
Peter A MerkelDivision of Rheumatology, Department of Medicine, and.ORCID 0000-0001-9284-7345
Michael WalshDivision of Nephrology, Department of Medicine.ORCID 0000-0001-8292-2014
PEXIVAS Investigators
Center for Rheumatology · USInstituto Nacional de Enfermedades Respiratorias · MXMayo Clinic · USMayo Clinic in Arizona · USPopulation Health Research Institute · CAThe Ohio State University · USUniversity of Cambridge · GB

Funding

Plasma Exchange and Glucocorticoids for Treatment of ANCA-Associated VasculitisR01FD003516 · FDA · UNIVERSITY OF PENNSYLVANIA · PI MERKEL, PETER A · 2009 to 2015
$1.6M
CIHR 159662CIHR 211079FDA HHS R01 FD003516NIAMS NIH HHS U54 AR0573319
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Neutrophil Cytoplasmic Antibody-Associated VasculitisGlucocorticoidsHemorrhagePlasma ExchangeAdultAgedFemaleHumansLung DiseasesMaleMiddle AgedPulmonary AlveoliRespiration, ArtificialTreatment OutcomeGlucocorticoidsdiffuse alveolar hemorrhageglucocorticoidsplasma exchangerespiratory failure

Identifiers

PMID38346237
PMCPMC11092964
OpenAlexW4391756746

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.