Evidence map›Paper›PMID 38346104›Full record

ReviewCirculation2024

Opportunities in the Postpartum Period to Reduce Cardiovascular Disease Risk After Adverse Pregnancy Outcomes: A Scientific Statement From the American Heart Association.

Jennifer Lewey, Theresa M Beckie, Haywood L Brown, Susan D Brown, Vesna D Garovic, Sadiya S Khan, Eliza C Miller, Garima Sharma, Laxmi S Mehta, American Heart Association Cardiovascular Disease and Stroke in Women and Underrepresented Populations Committee of the Council on Clinical Cardiology; Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation; and Council on Cardiovascular and Stroke Nursing

Registry-linked trialAbstract readReview
In one paragraph

Review in Circulation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07778966 (Alabama Womb to Heart Solution), which is not on this map. Cited by 116 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
116citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07778966 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Alabama Womb to Heart Solution: A Community-Based Cardiovascular Health Intervention After Hypertension in Pregnancy

TypeinterventionalSponsorUniversity of Alabama at BirminghamRan2026 to 2030Enrolled174ConditionsPregnancy-Associated Hypertension, Gestational Hypertension, Preeclampsia, EclampsiaArmsAlabama Womb to Heart Solution (AW2H) Community Health Worker (CHW) Program, Usual postpartum care with self-measured blood pressure education and home blood pressure monitor
3 · Its place in the literature

Who cites it

116 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Cardiovascular Health of Single Mothers: A Systematic Review.Journal of the American Heart Association · 2025
    Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Postpartum anthropometric and cardiovascular profile following hypertensive disorders of pregnancy: 12-month follow-up.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2026
    Article
  14. Hypertension Management in Pregnancy and Postpartum.Journal of the American Society of Nephrology : JASN · 2026
    Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Implementation strategies: bridging obstetrics and long-term care.American journal of obstetrics & gynecology MFM · 2026
    Review

56 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jennifer Lewey
Theresa M Beckie
Haywood L Brown
Susan D Brown
Vesna D Garovic
Sadiya S Khan
Eliza C Miller
Garima Sharma
Laxmi S Mehta
American Heart Association Cardiovascular Disease and Stroke in Women and Underrepresented Populations Committee of the Council on Clinical Cardiology; Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation; and Council on Cardiovascular and Stroke Nursing

Funding

Translational Research Core - Health Engagement & Action Translational (HEAT)P30DK092924 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI Alyce Sophia Adams, HILARY Kessler SELIGMAN · 2011 to 2026
$9.2M
Institutional Career Development CoreKL2TR003099 · NCATS · JOHNS HOPKINS UNIVERSITY · PI GEBO, KELLY A · 2019 to 2023
$7.9M
Preconception and Prenatal Health Impacting Factors and Child HealthUG3OD035540 · OD · KAISER FOUNDATION RESEARCH INSTITUTE · PI AVALOS, LYNDSAY AMMON, HEDDERSON, MONIQUE MARIE · 2023 to 2024
$6.4M
Vascular Contributions to Cognitive Impairment after Adverse Pregnancy Outcomes: the nuMoM2b-Heart Health StudyR01NS122815 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Eliza C Miller · 2021 to 2026
$3.7M
Optimizing a scalable intervention to maximize guideline-recommended diabetes testing after GDM - Diversity SupplementR01DK122087 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BROWN, SUSAN DENISE, FERRARA, ASSIAMIRA · 2021 to 2025
$3.6M
Motivational Determinants of Postpartum Lifestyle Behaviors, Weight Retention, and Metabolic SyndromeR01HL142996 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BROWN, SUSAN DENISE · 2019 to 2023
$3.0M
Cluster randomized trial of a mobile health intervention to achieve appropriate gestational weight gain in overweight/obese womenR01DK118455 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI HEDDERSON, MONIQUE MARIE · 2019 to 2023
$3.0M
Neurovascular Unit Dysfunction in Women with Severe PreeclampsiaK23NS107645 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MILLER, ELIZA C · 2019 to 2023
$1.1M
Obesity Prevention in Postpartum Women at High-Risk of Cardiovascular DiseaseK23HL153667 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI LEWEY, JENNIFER · 2020 to 2024
$926k
Mentoring Diverse Early Career Researchers in Behavioral Diabetes Prevention ResearchK26DK138246 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Susan Denise Brown · 2023 to 2026
$586k
Pregnancy complications and the development of Alzheimer's disease and related dementias in women in the Adult Changes in Thought studyR21AG069111 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MILLER, ELIZA C · 2020 to 2021
$460k
PROtecting Maternal brains from Injury and Stroke (PROMIS): a Single-center Phase 2 Clinical TrialR21HD110992 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MILLER, ELIZA C · 2023 to 2024
$452k
NCATS NIH HHS KL2 TR003099NHLBI NIH HHS K23 HL153667NHLBI NIH HHS R01 HL142996NIA NIH HHS R21 AG069111NICHD NIH HHS R21 HD110992NIDDK NIH HHS K26 DK138246NIDDK NIH HHS P30 DK092924NIDDK NIH HHS R01 DK118455NIDDK NIH HHS R01 DK122087NIH HHS UG3 OD035540NINDS NIH HHS K23 NS107645NINDS NIH HHS R01 NS122815
6 · The paper itself

Abstract

Adverse pregnancy outcomes are common among pregnant individuals and are associated with long-term risk of cardiovascular disease. Individuals with adverse pregnancy outcomes also have an increased incidence of cardiovascular disease risk factors after delivery. Despite this, evidence-based approaches to managing these patients after pregnancy to reduce cardiovascular disease risk are lacking. In this scientific statement, we review the current evidence on interpregnancy and postpartum preventive strategies, blood pressure management, and lifestyle interventions for optimizing cardiovascular disease using the American Heart Association Life's Essential 8 framework. Clinical, health system, and community-level interventions can be used to engage postpartum individuals and to reach populations who experience the highest burden of adverse pregnancy outcomes and cardiovascular disease. Future trials are needed to improve screening of subclinical cardiovascular disease in individuals with a history of adverse pregnancy outcomes, before the onset of symptomatic disease. Interventions in the fourth trimester, defined as the 12 weeks after delivery, have great potential to improve cardiovascular health across the life course.

Indexed as

Cardiovascular DiseasesAmerican Heart AssociationBlood PressureFemaleHumansPostpartum PeriodPregnancyPregnancy OutcomeRisk FactorsUnited StatesAHA Scientific Statementscardiovascular diseasesdiabetes, gestationalpostpartum periodpregnancypregnancy complicationsprimary prevention

Identifiers

PMID38346104
PMCPMC11185178

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.