Evidence map›Paper›PMID 38346011›Full record

ArticleJournal of the American Chemical Society2024

Synthetic Catalysts for Selective Glycan Cleavage from Glycoproteins and Cells.

Milad Zangiabadi, Foroogh Bahrami, Avijit Ghosh, Hai Yu, Anand Kumar Agrahari, Xi Chen, Yan Zhao

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Milad ZangiabadiDepartment of Chemistry, Iowa State University, Ames, Iowa 50011, United States.
Foroogh BahramiDepartment of Chemistry, Iowa State University, Ames, Iowa 50011, United States.
Avijit GhoshDepartment of Chemistry, Iowa State University, Ames, Iowa 50011, United States.ORCID 0000-0002-8974-9565
Hai YuDepartment of Chemistry, University of California-Davis, One Shields Avenue, Davis, California 95616, United States.ORCID 0000-0002-4378-0532
Anand Kumar AgrahariDepartment of Chemistry, University of California-Davis, One Shields Avenue, Davis, California 95616, United States.
Xi ChenDepartment of Chemistry, University of California-Davis, One Shields Avenue, Davis, California 95616, United States.ORCID 0000-0002-3160-614X
Yan ZhaoDepartment of Chemistry, Iowa State University, Ames, Iowa 50011, United States.ORCID 0000-0003-1215-2565

Funding

Supplement:Chemoenzymatic construction of synthetic human milk oligosaccharide (HMO) glycomeR01GM148568 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHEN, XI · 2022 to 2025
$1.4M
Artificial Glycosidase with Controlled SelectivityR01GM138427 · NIGMS · IOWA STATE UNIVERSITY · PI ZHAO, YAN · 2020 to 2023
$1.3M
Acquisition of a Q-Exactive Plus Mass SpectrometerS10OD025271 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JEWELL, WILLIAM T · 2019 to 2019
$486k
NIGMS NIH HHS R01 GM138427NIGMS NIH HHS R01 GM148568NIH HHS S10 OD025271
6 · The paper itself

Abstract

In situ modification of glycans requires extraordinary molecular recognition of highly complex and subtly different carbohydrates, followed by reactions at precise locations on the substrate. We here report synthetic catalysts that under physiological conditions cleave a predetermined oligosaccharide block such as a branched trimannose or the entire

Indexed as

GlycoproteinsPolysaccharidesGlycoside HydrolasesOligosaccharidesGlycoproteinsGlycoside HydrolasesOligosaccharidesPolysaccharides

Identifiers

PMID38346011
PMCPMC11103250

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.