Evidence map›Paper›PMID 38345751›Full record

SynthesisAging clinical and experimental research2024

Comparative efficacy of non-invasive brain stimulation for post-stroke cognitive impairment: a network meta-analysis.

Mengyu Yan, Jiarui Liu, Yiming Guo, Qingtao Hou, Jiaqi Song, Xiaoqin Wang, Weihua Yu, Yang Lü

Open access · hybridAbstract readSystematic ReviewComparative StudyNetwork Meta-Analysis
In one paragraph

Synthesis in Aging clinical and experimental research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mengyu Yan *Department of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yu Zhong District, , Chongqing, 400016, China.
Jiarui Liu *Department of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yu Zhong District, , Chongqing, 400016, China.
Yiming GuoInstitute of Neuroscience, Chongqing Medical University, No. 1 Yixuayuan Road, Yu Zhong District, Chongqing, 400016, China.
Qingtao HouDepartment of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yu Zhong District, , Chongqing, 400016, China.
Jiaqi SongInstitute of Neuroscience, Chongqing Medical University, No. 1 Yixuayuan Road, Yu Zhong District, Chongqing, 400016, China.
Xiaoqin WangDepartment of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yu Zhong District, , Chongqing, 400016, China.
Weihua YuInstitute of Neuroscience, Chongqing Medical University, No. 1 Yixuayuan Road, Yu Zhong District, Chongqing, 400016, China. yuweihua@cqmu.edu.cn.ORCID http://orcid.org/0000-0003-4865-4428
Yang LüDepartment of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yu Zhong District, , Chongqing, 400016, China. yanglyu@hospital.cqmu.edu.cn.
The Affiliated Yongchuan Hospital of Chongqing Medical University · CNChongqing Medical University · CN

Funding

Chongqing Talent Plan cstc2022ycjh-bgzxm0184National Key R&D Program of China 2020YFC2004200
6 · The paper itself

Abstract

backgroundNon-invasive brain stimulation (NIBS) is a burgeoning approach with the potential to significantly enhance cognition and functional abilities in individuals who have undergone a stroke. However, the current evidence lacks robust comparisons and rankings of various NIBS methods concerning the specific stimulation sites and parameters used. To address this knowledge gap, this systematic review and meta-analysis seek to offer conclusive evidence on the efficacy and safety of NIBS in treating post-stroke cognitive impairment.

methodsA systematic review of randomized control trials (RCT) was performed using Bayesian network meta-analysis. We searched RCT in the following databases until June 2022: Cochrane Central Register of Controlled Trials (CENTRAL), PUBMED, and EMBASE. We compared any active NIBS to control in terms of improving cognition function and activities of daily living (ADL) capacity following stroke.

resultsAfter reviewing 1577 retrieved citations, a total of 26 RCTs were included. High-frequency (HF)-repetitive transcranial magnetic stimulation (rTMS) (mean difference 2.25 [95% credible interval 0.77, 3.66]) was identified as a recommended approach for alleviating the global severity of cognition. Dual-rTMS (27.61 [25.66, 29.57]) emerged as a favorable technique for enhancing ADL function. In terms of stimulation targets, the dorsolateral prefrontal cortex exhibited a higher ranking in relation to the global severity of cognition.

conclusionsAmong various NIBS techniques, HF-rTMS stands out as the most promising intervention for enhancing cognitive function. Meanwhile, Dual-rTMS is highly recommended for improving ADL capacity.

Indexed as

Cognitive DysfunctionStrokeStroke RehabilitationActivities of Daily LivingCognitionHumansRandomized Controlled Trials as TopicTranscranial Magnetic StimulationTreatment OutcomeActivities of daily livingCognitionNetwork meta-analysisNon-invasive brain stimulationStroke

Identifiers

PMID38345751
PMCPMC10861650
OpenAlexW4391754351

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.