Evidence map›Paper›PMID 38345725›Full record

ArticleJapanese journal of radiology2024

Exploration of tumor size measurement methods in preoperative breast cancer assessment using whole-body silicon photomultiplier PET: feasibility and first results.

Hiroyuki Kuroda, Takeshi Yoshizako, Nobuhiro Yada, Tomomi Kamimura, Nobuko Yamamoto, Mitsunari Maruyama, Rika Yoshida, Mizuki Fukuda, Yuko Kataoka, Masayuki Itakura and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Japanese journal of radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Hiroyuki KurodaDepartment of Radiology, Faculty of Medicine, Shimane University, 89-1 Enya, 00693-8501, Izumo, Shimane, Japan. kurodax@med.shimane-u.ac.jp.ORCID http://orcid.org/0000-0001-5888-1881
Takeshi YoshizakoDepartment of Radiology, Faculty of Medicine, Shimane University, 89-1 Enya, 00693-8501, Izumo, Shimane, Japan.
Nobuhiro YadaDepartment of Radiology, Shimane University Hospital, Izumo, Shimane, Japan.
Tomomi KamimuraDepartment of Radiology, Faculty of Medicine, Shimane University, 89-1 Enya, 00693-8501, Izumo, Shimane, Japan.
Nobuko YamamotoDepartment of Radiology, Faculty of Medicine, Shimane University, 89-1 Enya, 00693-8501, Izumo, Shimane, Japan.
Mitsunari MaruyamaDepartment of Radiology, Faculty of Medicine, Shimane University, 89-1 Enya, 00693-8501, Izumo, Shimane, Japan.
Rika YoshidaDepartment of Radiology, Faculty of Medicine, Shimane University, 89-1 Enya, 00693-8501, Izumo, Shimane, Japan.
Mizuki FukudaDepartment of Radiology, Shimane University Hospital, Izumo, Shimane, Japan.
Yuko KataokaPathology Division, Faculty of Medicine, Shimane University, Izumo, Shimane, Japan.
Masayuki ItakuraDepartment of Digestive and General Surgery, Faculty of Medicine, Shimane University, Izumo, Shimane, Japan.
Yasushi KajiDepartment of Radiology, Faculty of Medicine, Shimane University, 89-1 Enya, 00693-8501, Izumo, Shimane, Japan.
Shimane University · JPShimane University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWhole-body silicon photomultiplier positron emission tomography (WB SiPM PET) could be used to diagnose breast cancer spread before lumpectomy. We aimed to investigate the method of measuring the tumor size by WB SiPM PET as a basis for diagnosing breast cancer spread in the breast. MATERIALS AND

methodsWe retrospectively reviewed 35 breast cancer lesions in 32 patients who underwent WB SiPM PET/CT in the prone position as preoperative breast cancer examinations from September 2020 to March 2022. In all cases, a 20-mm spherical VOI was placed in the normal mammary gland to measure the mean standardised uptake value (SUVmean) and the standard deviation (SD) of

resultsThe lesion detection sensitivity was 97% for WB SiPM PET. PET detected 34 lesions, excluding 4-mm ductal carcinomas in situ (DCIS). PET measurements at the '1.5 SUVmean + 2 SD' threshold demonstrated values closest to the pathological tumor sizes, including EIC. Moreover, '1.5 SUVmean + 2 SD' had the highest concordance (63%).

conclusionsThe study demonstrated that among various PET thresholds, the '1.5 SUVmean + 2 SD' threshold exhibited the best performance. However, even with this threshold, the concordance rate was limited to only 63%.

Indexed as

Breast NeoplasmsFeasibility StudiesFluorodeoxyglucose F18Positron Emission Tomography Computed TomographySiliconAdultAgedAged, 80 and overFemaleHumansMiddle AgedPositron-Emission TomographyPreoperative CareRadiopharmaceuticalsRetrospective StudiesTumor BurdenFluorodeoxyglucose F18RadiopharmaceuticalsSiliconBreast cancerProne positionSiPM PETTumor sizeWhole-body PET

Identifiers

PMID38345725
PMCPMC11139740
OpenAlexW4391749792

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.